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Detection of mpox virus in ambient air in a sexual health clinic

Tijdschriftbijdrage - Tijdschriftartikel

Although transmitted mainly through direct (sexual) contact, mpox virus (MPXV) can be detected in ambient air. We explored the use of air sampling for diagnosis or (genomic) surveillance of mpox in a sexual health clinic. For six out of six patients who were infected with MPXV, all four of our ambient air PCR tests were positive. For 14 uninfected patients, PCR was positive in three ambient air samples, albeit with higher cycle threshold (Ct) values. Genomic sequencing of samples from two positive patients showed matching sequences between air and clinical samples.

Tijdschrift: Archives of Virology
ISSN: 0304-8608
Issue: 8
Volume: 168
Jaar van publicatie:2023
Trefwoorden:Humans, Monkeypox virus, Sexual Health, Chromosome Mapping, Genomics, Polymerase Chain Reaction, Monkeypox