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Catalytic aerobic oxidation of $C(sp^{3})-H$ bonds

Tijdschriftbijdrage - Tijdschriftartikel

Oxidation reactions are a key technology to transform hydrocarbons from petroleum feedstock into chemicals of a higher oxidation state, allowing further chemical transformations. These bulk scale oxidation processes usually employ molecular oxygen as the terminal oxidant as at this scale it is typically the only economically viable oxidant. The produced commodity chemicals possess limited functionality and usually show a high degree of symmetry thereby avoiding selectivity issues. In sharp contrast in the production of fine chemicals preference is still given to classical oxidants. Considering the strive for greener production processes the use of O2, the most abundant and greenest oxidant, is a logical choice. Given the rich functionality and complexity of fine chemicals achieving regio/chemoselectivity is a major challenge. This review presents an overview of the most important catalytic systems recently described for aerobic oxidation, and the current insight in their reaction mechanism.
Tijdschrift: Angewandte Chemie: international edition in English
ISSN: 1433-7851
Volume: 58
Pagina's: 7946 - 7970
Jaar van publicatie:2019
Trefwoorden:A1 Journal article
BOF-publication weight:6
CSS-citation score:4
Authors from:Higher Education