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Assessing the application of latent class and latent profile analysis for evaluating the construct validity of complex posttraumatic stress disorder: cautions and limitations

Tijdschriftbijdrage - Tijdschriftartikel

Background: The diagnosis of complex posttraumatic stress disorder (CPTSD) has beensuggested for inclusion in the 11th version of the International Classification of Diseases(ICD-11), with support for its construct validity coming from studies employing Latent ClassAnalysis (LCA) and Latent Profile Analysis (LPA).Objective: The current study aimed to critically evaluate the application of the techniquesLCA and LPA as applied in previous studies to substantiate the construct validity of CPTSD.Method: Both LCA and LPA were applied systematically in one sample (n = 245), replicatingthe setup of previous studies as closely as possible. The interpretation of classes wasaugmented with the use of graphical visualization.Results: The LCA and LPA analyses indicated divergent results in the same dataset. LCA andLPA partially supported the existence of classes of patients endorsing different PTSD andCPTSD symptom patterns. However, further inspection of the results with scatterplots didnot support a clear distinction between PTSD and CPTSD, but rather suggested that there ismuch greater variability in clinical presentations amongst adult PTSD patients than can befully accounted for by either PTSD or CPTSD.Discussion: We argue that LCA and LPA may not be sufficient methods to decide on theconstruct validity of CPTSD, as different subgroups of patients are identified, depending onthe statistical exact method used and the interpretation of the fit of different models.Additional methods, including graphical inspection should be employed in future studies.
Tijdschrift: European Journal of Psychotraumatology
Issue: 1
Volume: 10
Pagina's: 1 - 11
Jaar van publicatie:2019
Trefwoorden:Psychiatrie en neurologie , Psychologie en gedragswetenschappen