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Amine activation

Tijdschriftbijdrage - Tijdschriftartikel

Ondertitel:synthesis of N‑(hetero)arylamides from isothioureas and carboxylic acids
A novel method for N-(hetero)arylamide synthesis based on rarely explored amine activation, rather than classical acid activation, is reported. The activated amines are easily prepared using a three-component reaction with commercial reagents. The new method shows a broad scope including challenging amides not (efficiently) accessible via classical protocols.
Tijdschrift: Organic letters
ISSN: 1523-7060
Volume: 18
Pagina's: 4602 - 4605
Jaar van publicatie:2016
Trefwoorden:A1 Journal article
BOF-publication weight:10
CSS-citation score:2
Authors from:Higher Education