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The Added Value of High Dose Spinal Cord Stimulation in Patients with Failed Back Surgery Syndrome after Conversion from Standard Spinal Cord Stimulation

Tijdschriftbijdrage - Tijdschriftartikel

Patients with Failed Back Surgery Syndrome (FBSS) report a considerably lower health- related quality of life (HRQoL), compared to the general population. Spinal cord stimulation (SCS) is an effective treatment to offer pain relief in those patients. Despite initial treatment success of SCS, its effect sometimes wears off over time. This study investigates the added value of high dose SCS (HD-SCS) in patients with unsatisfactory conventional SCS, from a quality of life perspective. Seventy-eight FBSS patients who were treated with conventional SCS that failed to provide pain relief, were recruited in 15 centers. HRQoL was assessed before converting to HD-SCS (baseline) and three times after converting to HD-SCS using the EuroQol-5D-3L. Quality adjusted life years (QALY) were calculated and compared with conventional SCS. An overall significant increase over time was seen in utility values of the EQ5D-3L, as the mean value at baseline 0.283 (±0.21) increased to 0.452 (±0.29) at 12 months of HD-SCS. This average increase in utility coincides with an average increase of 0.153 (±0.24) QALY's in comparison to continued conventional SCS. Besides the potential of HD-SCS to salvage patients with failed responses to conventional SCS, this treatment seems to be a more efficient treatment than conventional SCS.

Tijdschrift: Journal of Clinical Medicine
ISSN: 2077-0383
Issue: 10
Volume: 9
Pagina's: 1-11
Jaar van publicatie:2020
Trefwoorden:EQ5D-3L, chronic pain management, cohort study, failed back surgery syndrome, health-related quality of life;, high-dose spinal cord stimulation
  • DOI: https://doi.org/10.3390/jcm9103126
  • Scopus Id: 85112306136
  • ORCID: /0000-0003-0252-0600/work/82019486
  • ORCID: /0000-0002-2496-9209/work/82021060
  • ORCID: /0000-0002-2271-9855/work/82021290
  • WoS Id: 000586170000001
  • VABB Id: c:vabb:492974
CSS-citation score:1
Toegankelijkheid:Open