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Tools and methods for expression of membrane proteins
The present invention relates cells or cellular systems that express both a membrane protein and a binding domain directed to said membrane protein. Also, methods are provided that use such cells or cellular systems to produce higher amounts of said membrane proteins. Further, the cells or cellular systems can be used as tools for the structural and functional characterization of membrane proteins, as well as for screening and drug discovery efforts targeting membrane proteins.
Bron: ORCID, ORCID, EPO