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Octrooi

Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the method, and methods for using the cells

The invention is directed to methods for culturing cells so that the cells are induced to differentiate into cells that express a hepatic stellate phenotype and cells that express a hepatic sinusoidal endothelial phenotype. The invention is also directed to cells produced by the methods of the invention. The cells are useful, among other things, for treatment of liver deficiency, liver metabolism studies, and liver toxicity studies.
Octrooi-publicatienummer: US9777258
Jaar aanvraag: 2015
Jaar toekenning: 2017
Jaar van publicatie: 2017
Status: Toegewezen
Technologiedomeinen: Biotechnologie
Gevalideerd voor IOF-sleutel: Ja
Toegewezen aan: Associatie KULeuven