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3,4-diaminobenzenesulfonamide derivatives for inhibiting cell death

The present invention relates to a novel class of compounds having the structure of formula (I) and pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof. These compounds inhibit or reduce the non-apoptotic cell death forms ferroptosis and/or oxytosis rendering them useful for the treatment of various conditions disclosed herein.
Octrooi-publicatienummer: EP3218357
Bron: EPO
Jaar aanvraag: 2015
Jaar toekenning: 2020
Jaar van publicatie: 2020
Status: Toegewezen
Technologiedomeinen: Pharmaceuticals
Gevalideerd voor IOF-sleutel: Ja