Onderzoeker
Steven Strubbe
- Trefwoorden:Moleculaire biologie, Immunologie
- Disciplines:Adaptieve immunologie, Immunogenetica, Stamcelbiologie, Hematologie
Affiliaties
- Vakgroep Diagnostische Wetenschappen (Departement)
Lid
Vanaf1 okt 2018 → 25 sep 2022 - Vakgroep Klinische Biologie, Microbiologie en Immunologie (Departement)
Lid
Vanaf1 sep 2015 → 30 sep 2018
Projecten
1 - 1 of 1
- Gene-targeting van humane pluripotente stamcellen voor de studie van humane T cel ontwikkeling en immuundeficiëntiesVanaf1 jan 2016 → 31 dec 2019Financiering: FWO Strategische Onderzoeksbeurs
Publicaties
1 - 10 van 10
- Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development(2022)
Auteurs: Juliette Roels, Jolien Van Hulle, Marieke Lavaert, Anna Kuchmiy, Steven Strubbe, Tom Putteman, Bart Vandekerckhove, Georges Leclercq, Filip Van Nieuwerburgh, Lena Böhme, et al.
- In vitro model systems to study human T cell development(2022)Edition: 2Series: Methods in Molecular Biology (MIMB)
Auteurs: Nina Lambrechts, Kai Ling Liang, Imke Velghe, Steven Strubbe, Anne-Catherine Dolens, Tom Taghon, Remy Bosselut, Melanie S. Vacchio
Pagina's: 335 - 354 - In vitro modeling of SCID using primary patient cells(2021)
Auteurs: Steven Strubbe
- Modeling of human T cell development in vitro as a read-out for hematopoietic stem cell multipotency(2021)
Auteurs: Steven Strubbe, Tom Taghon
Pagina's: 2113 - 2122 - A tumor suppressor enhancer of PTEN in T-cell development and leukemia(2021)
Auteurs: L Tottone, O Lancho, JW Loh, A Singh, S Kimura, Anna Kuchmiy, Steven Strubbe, MA Lawlor, V da Silva-Diz, S Luo, et al.
Pagina's: 93 - 109 - A novel non-coding variant in DCLRE1C results in deregulated splicing and induces SCID through the generation of a truncated ARTEMIS protein that fails to support V(D)J recombination and DNA damage repair(2021)
Auteurs: Steven Strubbe, Marieke De Bruyne, Ulrich Pannicke, Elien Beyls, Bart Vandekerckhove, Georges Leclercq, Elfride De Baere, Victoria Bordon, Anne Vral, Klaus Schwarz, et al.
- Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia(2020)
Auteurs: Morgan Thénoz, B Szarzynska, M Landfors, Anna Kuchmiy, Steven Strubbe, Lindy Reunes, Filip Matthijssens, Wouter Van Loocke, B Erarslan-Uysal, P Richter-Pechanska, et al.
Pagina's: 274 - 289 - Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia(2020)Volume: 136
Auteurs: Morgan Thénoz, Bronislawa Szarzynska, Mattias Landfors, Anna Kuchmiy, Steven Strubbe, Lindy Reunes, Filip Matthijssens, Wouter Van Loocke, Marc R. Mansour, Utpal Dave, et al.
Aantal pagina's: 1 - Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development(2020)
Auteurs: Anna Kuchmiy, Matthias De Decker, Steven Strubbe, Marieke Lavaert, Georges Leclercq, Filip Van Nieuwerburgh, Pieter Van Vlierberghe, Tom Taghon
Pagina's: 1280 - 1292 - PHF6 expression levels impact human hematopoietic stem cell differentiation(2020)
Auteurs: Anne-Catherine Dolens, Steven Strubbe, Inge Van de Walle, Finola E. Moore, Suzanne Vanhauwaert, Filip Matthijssens, David M. Langenau, Pieter Van Vlierberghe, Tom Taghon