Onderzoeker
Sophie Janssens
- Trefwoorden (Ghent University):ongevouwen eiwitrespons, IRE1, dendritsche cel biologie
- Disciplines (Flanders Institute for Biotechnology):Analyse van next-generation sequence data, Adaptieve immunologie, Bacteriologie
- Disciplines (Ghent University):Cellulaire signaaltransmissie, Inflammatie, Aangeboren immuniteit, Intracellulaire compartimenten en transport
- Zie ook: Sophie Janssens (Universiteit Gent)
Affiliaties
- Vakgroep Inwendige ziekten en Pediatrie (Departement)
Lid
Vanaf1 okt 2018 → Heden - Janssens Lab (Onderzoeksgroep)
Verantwoordelijke
Vanaf1 mrt 2018 → Heden - Lambrecht and Hammad Lab (Onderzoeksgroep)
Lid
Vanaf1 jan 2017 → 28 feb 2018 - Vakgroep Inwendige ziekten (Departement)
Lid
Vanaf1 mrt 2011 → 30 sep 2018 - Vakgroep Biomedische Moleculaire Biologie (Departement)
Lid
Vanaf1 apr 1998 → 30 sep 2007
Projecten
1 - 4 of 4
- Broadening the therapeutic window of LNP-based vaccination.Vanaf1 jun 2024 → HedenFinanciering: HORIZON.1.1 - European Research Council (ERC)
- VIB Grant for Janssens Lab_Period:2022-01-01-2026-12-31Vanaf1 jan 2022 → HedenFinanciering: VOI - Projectmatig onderzoek
- A novel physiological role for IRE1 and RIDD..., maintaining the balance between tolerance and immunity?Vanaf1 feb 2019 → 31 jan 2024Financiering: HORIZON.1.1 - European Research Council (ERC)
- VIB Grant for Janssens Lab_Period:2018-01-01-2021-12-31Vanaf1 jan 2018 → 31 dec 2021Financiering: VOI - Projectmatig onderzoek
Publicaties
1 - 10 van 40
- Type 1 immunity enables neonatal thymic ILC1 production.(2024)
Auteurs: Peter Tougaard, Mario Ruiz Pérez, Wolf Steels, Jelle Huysentruyt, Jessica Vetters, Amanda Gonçalves, Nozomi Takahashi, Sophie Janssens, Peter Vandenabeele
Pagina's: eadh5520 - Activation of goblet-cell stress sensor IRE1ß is controlled by the mucin chaperone AGR2.(2024)
Auteurs: Eva Cloots, Phaedra Guilbert, Savvas Savvides, Sven Eyckerman, Sophie Janssens
Pagina's: e-pub - Loss of function of XBP1 splicing activity of IRE1a favors B cell tolerance breakdown.(2024)
Auteurs: Laurien Van Heddegem, Victor Bosteels, Sandra Maréchal, Sophie Janssens
Pagina's: 103152 - The IRE1ß-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells.(2024)
Auteurs: Eva Cloots, Sophie Janssens
Pagina's: e-pub - Decoding immunogenic cell death from a dendritic cell perspective.(2024)
Auteurs: Sophie Janssens, Sofie Rennen, Patrizia Agostinis
Pagina's: e-pub - Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.(2023)
Auteurs: Jessica Vetters, Sofie Rennen, Eva Cloots, Bart Lambrecht, Sophie Janssens
Pagina's: 108570 - LXR signaling controls homeostatic dendritic cell maturation.(2023)
Auteurs: Victor Bosteels, Sandra Maréchal, Sofie Rennen, Jonathan Maelfait, Simon Tavernier, Jessica Vetters, Julie Van Duyse, Cédric Bosteels, Ria Roelandt, Annelies Emmaneel, et al.
Pagina's: eadd3955 - STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity.(2023)
Auteurs: Bastiaan Maes, Hamida Hammad, Sophie Janssens, Bart Lambrecht
Pagina's: e20210788 - Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity.(2023)
Auteurs: Sofie Rennen, Sophie Janssens
Pagina's: 1209588 - The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice.(2022)
Auteurs: Bastiaan Maes, Ursula Smole, Matthias Vanderkerken, Nincy Debeuf, Benjamin Pavie, Sophie Janssens, Savvas Savvides, Bart Lambrecht, Hamida Hammad
Pagina's: 1413-1427.e2