Onderzoeker
Sarah El Kharraz
- Disciplines (Flanders Institute for Biotechnology):Analyse van next-generation sequence data, Celdood, Kankerbiologie
- Disciplines (KU Leuven):Biochemie en metabolisme, Medische systeembiologie, Moleculaire en celbiologie, Oncologie
Affiliaties
- Laboratorium voor Cellulair Metabolisme en Metabole Regeling (VIB-KU Leuven) (Afdeling)
Lid
Vanaf8 aug 2022 → Heden - Fendt Lab (Onderzoeksgroep)
Lid
Vanaf8 aug 2022 → 31 dec 2023 - Laboratorium voor Moleculaire Endocrinologie (Afdeling)
Lid
Vanaf1 sep 2017 → 7 aug 2022
Projecten
1 - 1 of 1
- Wat is de rol van de dimerisatie van de receptor tijdens de werking van androgenen?Vanaf5 sep 2017 → 19 mei 2022Financiering: FWO mandaten
Publicaties
1 - 8 van 8
- Testosterone Restores Body Composition, Bone Mass, and Bone Strength Following Early Puberty Suppression in a Mouse Model Mimicking the Clinical Strategy in Trans Boys(2023)
Auteurs: Stefanie Doms, Sarah El Kharraz, Vera Maria Johanna Sommers, Karel David, Christa Maes, Leen Antonio, Brigitte Decallonne, Geert Carmeliet, Frank Claessens, Dirk Vanderschueren
Pagina's: 1497 - 1508 - A disease-associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer(2022)
Auteurs: Elien Smeets, Xiao Yin Lee, Christine Helsen, Sarah El Kharraz, Roy Eerlings, Stephanie Humblet-Baron, Arnout Voet, Anne Rochtus, Ann Van Schepdael, Francis de Zegher, et al.
Pagina's: 2242 - 2253 - N/C interactions are dispensable for normal in vivo functioning of the androgen receptor in male mice(2022)
Auteurs: Sarah El Kharraz, Vanessa Dubois, Elien Smeets, Roy Eerlings, Dirk Vanderschueren, Christine Helsen, Frank Claessens
- The role of receptor dimerization in androgen action: uncovering its physiological relevance using knockin mouse models(2022)
Auteurs: Sarah El Kharraz, Frank Claessens, Christine Helsen
- Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer(2022)
Auteurs: Lisa Moris, Bram Boeckx, Diether Lambrechts, Christine Helsen, Bart Ghesquière, Stefaan Soenen, Elien Smeets, Roy Eerlings, Sarah El Kharraz, Hendrik Van Poppel, et al.
Pagina's: 527 - 541 - Small-molecule profiling for steroid receptor activity using a universal steroid receptor reporter assay(2022)
Auteurs: Roy Eerlings, Tien Nguyen, Elien Smeets, Lisa Moris, Sarah El Kharraz, Arnout Voet, Wim Dehaen, Frank Claessens, Christine Helsen
- The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation.(2021)
Auteurs: Sarah El Kharraz, Vanessa Dubois, Tien Nguyen, Arnout Voet, Roy Eerlings, Stefan Prekovic, Elien Smeets, Lisa Moris, Kevin Verstrepen, Geert Carmeliet, et al.
Pagina's: 1 - 19 - Drivers of AR indifferent anti-androgen resistance in prostate cancer cells(2019)
Auteurs: Florian Handle, Stefan Prekovic, Christine Helsen, Thomas Van den Broeck, Elien Smeets, Lisa Moris, Roy Eerlings, Sarah El Kharraz, Steven Joniau, Frank Claessens