Onderzoeker
Sandra Van Lint
- Trefwoorden:mRNA, immunologie, Dendritische cellen, kanker, T-cellen, tumor micro-omgeving, adaptief immuunsysteem
- Disciplines:Immunologie niet elders geclassificeerd, Vaccinologie, Kankertherapie, Transcriptie en translatie, Cellulaire signaaltransmissie, Adaptieve immunologie, Toegepaste immunologie, Kankerbiologie, Immunogenetica, Aangeboren immuniteit, Kankerpreventie
Affiliaties
- Vakgroep Inwendige ziekten en Pediatrie (Departement)
Lid
Vanaf1 jan 2021 → Heden - Vakgroep Biomoleculaire Geneeskunde (Departement)
Lid
Vanaf1 okt 2018 → 31 dec 2020 - Vakgroep Biochemie (Departement)
Lid
Vanaf1 feb 2015 → 30 sep 2018
Projecten
1 - 1 of 1
- AcTakine-gebaseerde kanker therapieVanaf1 okt 2015 → 30 sep 2018Financiering: BOF - Andere acties
Publicaties
1 - 10 van 32
- Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials(2022)
Auteurs: Joline Ingels, Laurenz De Cock, Rupert Mayer, Pam Devreker, Karin Weening, Nele Lootens, Saskia De Smet, Marieke Brusseel, Stijn De Munter, Melissa Pille, et al.
Pagina's: 213 - 222 - Dendritic cell-based immunotherapy in lung cancer(2021)
Auteurs: Dieter Stevens, Joline Ingels, Sandra Van Lint, Bart Vandekerckhove, Karim Vermaelen
- Selective IL-1 activity on CD8+ T cells empowers antitumor immunity and synergizes with neovasculature-targeted TNF for full tumor eradication(2021)
Auteurs: Bram Van Den Eeckhout, Leander Huyghe, Sandra Van Lint, Elianne Burg, Stéphane Plaisance, Frank Peelman, Anje Cauwels, Gilles Uzé, Niko Kley, Sarah Gerlo, et al.
- Targeting IFN activity to both B cells and plasmacytoid dendritic cells induces a robust tolerogenic response and protection against EAE(2021)
Auteurs: Anje Cauwels, Sandra Van Lint, Elke Rogge, Annick Verhee, Bram Van Den Eeckhout, Shengru Pang, Marco Prinz, Niko Kley, Gilles Uze, Jan Tavernier
- mRNA in cancer immunotherapy : beyond a source of antigen(2021)
Auteurs: Lien Van Hoecke, Rein Verbeke, Heleen Dewitte, Sabine Lentacker, Karim Vermaelen, Karine Breckpot, Sandra Van Lint
- Specific targeting of IL-1U+03B2 activity to CD8+ T cells allows for safe use as a vaccine adjuvant(2020)
Auteurs: Bram Van Den Eeckhout, Lien Van Hoecke, Elianne Burg, Sandra Van Lint, Frank Peelman, Niko Kley, Gilles Uzé, Xavier Saelens, Jan Tavernier, Sarah Gerlo
- The opposing effect of type I IFN on the T cell response by non-modified mRNA-lipoplex vaccines Is determined by the route of administration(2020)
Auteurs: Lien Van Hoecke, Kenny Roose, Marlies Ballegeer, Zifu Zhong, Niek Sanders, Stefaan De Koker, Xavier Saelens, Sandra Van Lint
Pagina's: 373 - 381 - Targeting interferon activity to dendritic cells enables in vivo tolerization and protection against EAE in mice(2019)
Auteurs: Anje Cauwels, Sandra Van Lint, Dominiek Catteeuw, Shengru Pang, Franciane Paul, Elke Rogge, Annick Verhee, Marco Prinz, Niko Kley, Gilles Uzé, et al.
Pagina's: 70 - 76 - Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes(2018)
Auteurs: Lien Van Hoecke, Sandra Van Lint, Kenny Roose, Alexander Van Parys, Peter Vandenabeele, Johan Grooten, Jan Tavernier, Stefaan De Koker, Xavier Saelens
- Nanoparticle-conjugate TLR7/8 agonist localized immunotherapy provokes safe antitumoral responses(2018)
Auteurs: Lutz Nuhn, Stefaan De Koker, Sandra Van Lint, Zifu Zhong, João Portela Catani, Francis Combes, Kim Deswarte, Yupeng Li, Bart Lambrecht, Stefan Lienenklaus, et al.