Onderzoeker
Ruben Boon
- Disciplines:Genetica, Systeembiologie, Moleculaire en celbiologie, Morfologische wetenschappen, Oncologie
Affiliaties
- Laboratorium voor Functionele Epigenetica (Afdeling)
Lid
Vanaf1 sep 2021 → 31 jan 2022 - Stamcel- en Ontwikkelingsbiologie (Afdeling)
Lid
Vanaf1 apr 2013 → 31 dec 2018
Projecten
1 - 1 of 1
- Metabolomics van stamceldifferentiatie.Vanaf13 aug 2012 → 13 dec 2017Financiering: IWT persoonsgebonden financ. - strategische onderzoeksbeurzen
Publicaties
1 - 10 van 31
- A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes(2022)
Auteurs: Manoj Gautam, Tine Tricot, Ruben Boon, Burak Toprakhisar, Catherine Verfaillie
Pagina's: 702 - 712 - Metabolic Fuel for Epigenetic: Nuclear Production Meets Local Consumption(2021)
Auteurs: Ruben Boon
- A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model(2021)
Auteurs: Manoj Gautam, Burak Toprakhisar, Matthias Van Haele, Ruben Boon, Tine Tricot, Jolan De Boeck, Adrian Ranga, Francesca Maria Bosisio, Tania Roskams, Catherine Verfaillie
- HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations(2021)
Auteurs: Raheem Fazal, Mathias De Decker, Laura Fumagalli, Joni Vanneste, Wenting Guo, Ruben Boon, Thomas Vercruysse, Bart Swinnen, Jimmy Beckers, Pieter Vanden Berghe, et al.
- A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma(2021)
Auteurs: Ruben Boon
Pagina's: 182 - + - PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells(2021)
Auteurs: Jonathan De Smedt, Sreya Hillol Ghosh, Burak Toprakhisar, Rodrigo Furtado Madeiro Da Costa, Samantha Zaunz, Ruben Boon, Catherine Verfaillie
- Nuclear metabolism and the regulation of the epigenome(2020)
Auteurs: Ruben Boon
Pagina's: 1190 - 1203 - Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines(2020)
Auteurs: Ruben Boon, Manoj Gautam, Tine Tricot, Ilaria Elia, Jonathan De Smedt, Guy Eelen, Matthew Bird, Philip Roelandt, Ginevra Doglioni, Matteo Rossi, et al.
- Breast cancer cells rely on environmental pyruvate to shape the metastatic niche(2019)
Auteurs: Ilaria Elia, Matteo Rossi, Steve Stegen, Dorien Broekaert, Ginevra Doglioni, Ruben Boon, Catherine Verfaillie, Eric Verbeken, Gertrudis Carmeliet, Sarah-Maria Fendt
Pagina's: 117 - + - Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2(2019)
Auteurs: Christel Claes, Johanna Van Den Daele, Ruben Boon, Mark Fiers, FatemehArefeh Nami, Bart De Strooper, Catherine Verfaillie
Pagina's: 453 - 464
Patenten
1 - 4 van 4
- Methods for differentiating cells into hepatic stellate cells (Inventor)
- Cell culture media for differentiation of stem cells into hepatocytes (Inventor)
- Cell culture media for differentiation of stem cells into hepatocytes (Inventor)
- Methods for differentiating cells into hepatic stellate cells (Inventor)