Onderzoeker
Robin Maximilian Awad
- Onderzoeksexpertise:
Expertise: Tumor immunology.
We evaluate the use of single domain antibodies (sdAbs), also known as nanobodies, as targeting moieties for therapeutic and diagnostic applications.
- Trefwoorden:Geneeskunde
- Disciplines:Toegepaste immunologie, Kankertherapie
- Gebruikers van onderzoeksexpertise:
Expertise: Tumor immunology.
We evaluate the use of single domain antibodies (sdAbs), also known as nanobodies, as targeting moieties for therapeutic and diagnostic applications.
Affiliaties
- Laboratorium voor Moleculaire en Cellulaire Therapie (Onderzoeksgroep)
Lid
Vanaf19 mrt 2021 → Heden - Faculteit van de Geneeskunde en Farmacie (Faculteit)
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Vanaf11 sep 2018 → Heden - Basis (bio)-medische wetenschappen (Departement)
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Vanaf1 nov 2019 → Heden - Basis (bio)-medische wetenschappen (Departement)
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Vanaf8 apr 2019 → 31 okt 2019 - Basis (bio)-medische wetenschappen (Departement)
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Vanaf1 okt 2018 → 31 okt 2019 - Faculteit van de Geneeskunde en Farmacie (Faculteit)
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Vanaf30 sep 2015 → 27 jun 2018
Projecten
1 - 1 of 1
- Versterken van de functie van kanker tegenwerkende effector cellen met behulp van nanobodies specifiek voor regulerende immuun controle puntenVanaf1 nov 2019 → 31 okt 2021Financiering: FWO mandaten
Publicaties
1 - 10 van 12
- Targeted α-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment(2023)
Auteurs: T Ertveldt, Ahmet Krasniqi, Hannelore Ceuppens, Janik Puttemans, Yana Dekempeneer, Kevin De Jonghe, Wout de Mey, Q Lecocq, Yannick De Vlaeminck, R M Awad, et al.
Pagina's: 751-758 - Junctional adhesion molecule-A is dispensable for myeloid cell recruitment and diversification in the tumor microenvironment(2022)
Auteurs: Máté Kiss, Els Lebegge, Aleksandar Murgaski, Helena Van Damme, Daliya Kancheva, Jan Brughmans, Isabelle Scheyltjens, Ali Talebi, R M Awad, Yvon Elkrim, et al.
- Targeted radionuclide therapy with low and high-dose Lutetium-177 labeled single domain antibodies induces distinct immune signatures in a mouse melanoma model(2022)
Auteurs: T Ertveldt, Lien De Beck, Kirsten De Ridder, Hanne Locy, Wout de Mey, Cleo Goyvaerts, Q Lecocq, Hannelore Ceuppens, Yannick De Vlaeminck, R M Awad, et al.
Pagina's: 1136-1148 - Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma(2022)
Auteurs: Lien De Beck, R M Awad, Veronica Basso, Noelia Casares, Kirsten De Ridder, Yannick De Vlaeminck, Alessandra Gnata, Cleo Goyvaerts, Q Lecocq, Edurne San José-Enériz, et al.
Pagina's: 1-15 - TNF-alpha-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy(2022)
Auteurs: Kirsten De Ridder, Hanne Locy, Elisa Piccioni, Miren Ibarra Zuazo, R M Awad, Stefaan Verhulst, Mathias Van Bulck, Yannick De Vlaeminck, Q Lecocq, Eva Reijmen, et al.
Pagina's: 1-15 - Novel 3D Lung Tumor Spheroids for Oncoimmunological Assays(2022)
Auteurs: Kirsten De Ridder, Navpreet Tung, Jan-Timon Werle, Léa Karpf, R M Awad, Annie Bernier, Hannelore Ceuppens, Hélène Salmon, Cleo Goyvaerts
- Emerging applications of nanobodies in cancer therapy(2022)
Auteurs: R M Awad, Fien Meeus, Hannelore Ceuppens, T Ertveldt, Heleen Hanssens, Q Lecocq, Lukasz Mateusiak, Katty Zeven, Hana Valenta, Timo W M De Groof, et al.
Pagina's: 143-199 - Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer(2021)
Auteurs: Q Lecocq, Pieterjan Debie, Janik Puttemans, R M Awad, Lien De Beck, T Ertveldt, Yannick De Vlaeminck, Cleo Goyvaerts, G Raes, M Keyaerts, et al.
- Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade(2021)
Auteurs: Q Lecocq, R M Awad, Yannick De Vlaeminck, Wout de Mey, T Ertveldt, Cleo Goyvaerts, G Raes, Kris Thielemans, M Keyaerts, Nick Devoogdt, et al.
Pagina's: 1638-1644 - Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade(2021)
Auteurs: R M Awad, Q Lecocq, Katty Zeven, T Ertveldt, Lien De Beck, Hannelore Ceuppens, Katrijn Broos, Yannick De Vlaeminck, Cleo Goyvaerts, M Verdonck, et al.
Pagina's: 172-182