Onderzoeker
Luping Pang
- Disciplines:Ontdekking en evaluatie van biomarkers, Ontdekking en evaluatie van geneesmiddelen, Medicinale producten, Farmaceutica, Farmacognosie en fytochemie, Farmacologie, Farmacotherapie, Toxicologie en toxinologie, Andere farmaceutische wetenschappen, Bio-informatica en computationele biologie
Affiliaties
- Medicinale Chemie (Rega Instituut) (Afdeling)
Lid
Vanaf1 sep 2016 → 31 aug 2022
Projecten
1 - 1 of 1
- Structurele en functionele studies van antibiotica producerende eiwittenVanaf1 okt 2016 → 23 sep 2020Financiering: Eigen Middelen zoals patrimonium, inschrijvingsgelden, giften, ....
Publicaties
1 - 10 van 13
- Towards Novel 3-Aminopyrazinamide-Based Prolyl-tRNA Synthetase Inhibitors: In Silico Modelling, Thermal Shift Assay and Structural Studies(2021)
Auteurs: Luping Pang, Sergei Strelkov, Arthur Van Aerschot
- Aminoacyl-tRNA Synthetases as Valuable Targets for Antimicrobial Drug Discovery.(2021)
Auteurs: Luping Pang, Arthur Van Aerschot
- Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors(2021)
Auteurs: Dries De Ruysscher, Luping Pang, Stijn Lenders, Jef Rozenski, Sergei Strelkov, Arthur Van Aerschot
- Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors(2020)
Auteurs: Luping Pang, Steff De Graef, Eveline Lescrinier, Jef Rozenski, Sergei Strelkov, Arthur Van Aerschot
- Structural Characterization of Aminoacyl-tRNA Synthetase Inhibitors as Antibiotics and Tools for Enzyme Mechanistic Studies(2020)
Auteurs: Luping Pang, Arthur Van Aerschot, Sergei Strelkov, Stephen Weeks
- Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase(2020)
Auteurs: Luping Pang, Steff De Graef, Sergei Strelkov, Arthur Van Aerschot
- Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase(2020)
Auteurs: Dries De Ruysscher, Luping Pang, Charles-Alexandre Mattelaer, Steff De Graef, Jef Rozenski, Sergei Strelkov, Eveline Lescrinier, Arthur Van Aerschot
- Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases(2020)
Auteurs: Luping Pang, Steff De Graef, Valentina Zorzini, Tassos Economou, Sergei Strelkov, Arthur Van Aerschot
Pagina's: 407 - 415 - Synthesis and Biological Evaluation of Lipophilic Nucleoside Analogues as Inhibitors of Aminoacyl-tRNA Synthetases(2019)
Auteurs: Manesh Nautiyal, Steff De Graef, Luping Pang, Jef Rozenski, Arthur Van Aerschot
- Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily(2019)
Auteurs: Dries De Ruysscher, Luping Pang, Steff De Graef, Manesh Nautiyal, Wim De Borggraeve, Jef Rozenski, Sergei Strelkov, Stephen Weeks, Arthur Van Aerschot
Pagina's: 252 - 264