Onderzoeker
Luc Bouwens
- Onderzoeksexpertise:
- In vitro and in vivo models to induce islet regeneration or islet cell neogenesis and in which the effect of soluble growth factors, hormones, cytokines or pharmacological substances can be studied
- Regenerative medicine for diabetes
- Trefwoorden:Geneeskunde
- Disciplines:Metabole ziekten, Gastro-enterologie, Celdood, Stamcelbiologie, Histologie, Celtherapie, Weefselengineering
- Gebruikers van onderzoeksexpertise:
- In vitro and in vivo models to induce islet regeneration or islet cell neogenesis and in which the effect of soluble growth factors, hormones, cytokines or pharmacological substances can be studied
- Regenerative medicine for diabetes
Affiliaties
- Celdifferentiatie (Onderzoeksgroep)
Verantwoordelijke
Vanaf30 sep 2002 → Heden - Basis (bio)-medische wetenschappen (Departement)
Lid
Vanaf1 okt 2019 → 20 mei 2020 - Basis (bio)-medische wetenschappen (Departement)
Verantwoordelijke
Vanaf1 jan 2014 → 30 sep 2022 - Celdifferentiatie (Onderzoeksgroep)
Lid
Vanaf31 mei 2002 → 31 mei 2011 - Pathologische Anatomie (Departement)
Lid
Vanaf1 feb 1993 → 31 dec 2013 - Celbiologie en Histologie (Departement)
Verantwoordelijke
Vanaf1 okt 1987 → 31 jan 1993
Projecten
1 - 7 of 7
- FWO Hercules MZW: ERA platform: Extensief RNA Analyse platformVanaf1 mei 2018 → 30 apr 2022Financiering: FWO Middelzware apparatuur
- Pancreatische acinaire cel reprogrammering voor betacel regeneratieVanaf1 jan 2015 → 31 dec 2018Financiering: FWO Onderzoeksproject
- SRP (Groeiers): Regenerative therapy in diabetesVanaf1 mrt 2014 → 28 feb 2019Financiering: BOF - Geconcert. Onderzoeksacties vanaf 1994
- Tracering en regulatie van delta naar beta-cel conversieVanaf1 okt 2012 → 30 dec 2019Financiering: FWO mandaten
- Stimulatie van betacel progenitoren in diabetische pancreas.Vanaf1 jan 2010 → 31 dec 2013Financiering: FWO Onderzoeksproject
- De rol van Geminine in de ontwikkeling van de pancreas.Vanaf1 jan 2010 → 31 dec 2013Financiering: FWO Onderzoeksproject
- Multifoon confocale laser scanning microscoop voor imaging core faciliteit ter ondersteuning van onderzoek van de life sciences campus Jette en campus etterbeek -VUB.Vanaf1 dec 2008 → 30 nov 2013Financiering: Hercules - Kleine en middelzware apparatuur
Publicaties
1 - 10 van 67
- Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation(2022)
Auteurs: Karen De Vlaminck, Hannah Van Hove, Daliya Kancheva, Isabelle Scheyltjens, Ana Rita Pombo Antunes, Jonathan Bastos, Mónica Vara Pérez, Leen Ali, Myrthe Mampay, Lauren Deneyer, et al.
Pagina's: 2085-2102.e9 - Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease(2022)
Auteurs: Sandrina Martens, Katarina Coolens, Mathias Van Bulck, Tatjana Arsenijevic, Joan Casamitjana, Angel Fernandez Ruiz, Abdessamad El Kaoutari, Jaime Martinez de Villareal, Hediel Madhloum, Farzad Esni, et al.
Pagina's: 2030-2042 - In vitro comparison of various antioxidants and flavonoids from Rooibos as beta cell protectants against lipotoxicity and oxidative stress-induced cell death(2022)
Auteurs: Céline Moens, Christo J. F. Muller, Luc Bouwens
- Transcutaneous Vagal Nerve Stimulation Alone or in Combination With Radiotherapy Stimulates Lung Tumor Infiltrating Lymphocytes But Fails to Suppress Tumor Growth(2021)
Auteurs: Eva Reijmen, Sven de Mey, Helena Van Damme, Kirsten De Ridder, Thierry Gevaert, Emmy De Blay, Luc Bouwens, Christine Collen, Lore Decoster, Marijke De Couck, et al.
- Fractionated Radiation Severely Reduces the Number of CD8+ T Cells and Mature Antigen Presenting Cells Within Lung Tumors(2021)
Auteurs: Eva Reijmen, Sven de Mey, Wout De Mey, Thierry Gevaert, Kirsten De Ridder, Hanne Locy, Sandrina Martens, Emmy De Blay, Luc Bouwens, Pieterjan Debie, et al.
Pagina's: 272-283 - MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions(2021)
Auteurs: Elyne Backx, Elke Wauters, Jonathan Baldan, Mathias Van Bulck, Ellis Michiels, Yves Heremans, Diedert Luc De Paep, Mineo Kurokawa, Susumu Goyama, Luc Bouwens, et al.
Pagina's: 2601-2615 - MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions(2021)
Auteurs: Elyne Backx, Elke Wauters, Jonathan Baldan, Mathias Van Bulck, Ellis Michiels, Y Heremans, Diedert Luc De Paep, Mineo Kurokawa, Susumu Goyama, Luc Bouwens, et al.
Pagina's: 2601-2615 - Dynamic regulation of expression of KRAS and its effectors determines the ability to initiate tumorigenesis in pancreatic acinar cells(2021)
Auteurs: Mohamad Nabil Assi, Younes Achouri, Axelle Loriot, Nicolas Dauguet, Hajar Dahou, Jonathan Baldan, Maxime Libert, Jean S Fain, Carmen Guerra, Luc Bouwens, et al.
Pagina's: 2679-2689 - Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization(2021)
Auteurs: Ana Rita Pombo Antunes, Isabelle Scheyltjens, Francesca Lodi, Julie Messiaen, Asier Antoranz, Johnny Duerinck, Daliya Kancheva, Liesbet Martens, Karen De Vlaminck, Hannah Van Hove, et al.
Pagina's: 595-610 - Peroxiredoxin-I sustains inflammation during pancreatitis(2021)
Auteurs: Hortense Buckens, Sophie Pirenne, Younes Achouri, Jonathan Baldan, Hajar Dahou, Luc Bouwens, Frédéric P Lemaigre, Patrick Jacquemin, Mohamad Assi
Pagina's: 741-743