Onderzoeker
Laurens Léger
- Disciplines:Stamcelbiologie
Affiliaties
- Vakgroep Structuur en Herstel van de Mens (Departement)
Lid
Vanaf1 okt 2019 → 22 sep 2024
Projecten
1 - 1 of 1
- Moleculaire mechanismen die aan de basis liggen van aritmogene cardiomyopathie gebruik makende van geconstrueerd hartweefselVanaf16 jan 2023 → 15 okt 2023Financiering: BOF - doctorale mandaten
Publicaties
1 - 10 van 13
- Three-dimensional co-culturing of stem cell-derived cardiomyocytes and cardiac fibroblasts reveals a role for both cell types in Marfan-related cardiomyopathy(2024)
Auteurs: Jeffrey Aalders, Laurens Léger, Louis Van der Meeren, Sanjay Sinha, Andre Skirtach, Julie De Backer, Jolanda van Hengel
Pagina's: 14 - 24 - Photoporation-mediated spatial intracellular delivery of stem cell-derived cardiomyocytes(2024)
Auteurs: Laurens Léger, Chloë De Clercq, Jeffrey Aalders, Kevin Braeckmans, Jolanda van Hengel
- Combinatorial effects of surface plasma-treating and aligning PCL/chitosan nanofibers on the behavior of stem cell-derived cardiomyocytes for cardiac tissue engineering(2024)
Auteurs: Laurens Léger, Sheida Aliakbarshirazi, Pegah Zahedifar, Jeffrey Aalders, Pascal Van Der Voort, Nathalie De Geyter, Rino Morent, Jolanda van Hengel, Rouba Ghobeira
- Improving cardiac differentiation of human pluripotent stem cells by targeting ferroptosis(2024)
Auteurs: Jeffrey Aalders, Laurens Léger, Behrouz Hassannia, Vera Goossens, Tom Vanden Berghe, Jolanda van Hengel
Pagina's: 21 - 31 - Generation of human induced pluripotent stem cell line UGENTi001-A from a patient with Marfan syndrome carrying a heterozygous c.7754 T > C variant in FBN1 and the isogenic control UGENT001-A-1 using CRISPR/Cas9 editing(2023)
Auteurs: Jeffrey Aalders, Laurens Léger, Anthony Demolder, Laura Muiño Mosquera, Paul Coucke, Björn Menten, Julie De Backer, Jolanda van Hengel
- In vitro modelling of Marfan-related cardiomyopathy points to abnormalities in mechanobiology of the heart muscle cells(2022)
Auteurs: Jeffrey Aalders, Laurens Léger, Louis Van der Meeren, Patrick Sips, Laura Muiño Mosquera, Andre Skirtach, Sanjay Sinha, Julie De Backer, Jolanda van Hengel
Aantal pagina's: 1 - Photothermal nanofibres enable safe engineering of therapeutic cells(2021)
Auteurs: Ranhua Xiong, Dawei Hua, Jelter Van Hoeck, Dominika Berdecka, Laurens Léger, Stijn De Munter, Juan Fraire, Laurens Raes, Aranit Harizaj, Félix Sauvage, et al.
Pagina's: 1281 - 1291 - Use of transparent liquid marble : microbioreactor to culture cardiospheres(2021)Series: Methods in Molecular Biology
Auteurs: Jeffrey Aalders, Laurens Léger, Davide Piras, Jolanda van Hengel, Sergio Ledda, Tiziana Brevini, Alireza Fazeli, Kursad Turksen
Pagina's: 85 - 102 - In vitro modelling of Marfan related cardiomyopathy points to abnormalities in mechanobiology of the heart muscle cells(2021)
Auteurs: Jeffrey Aalders, Laurens Léger, Louis Van der Meeren, Natasja Van den Vreken, Andre Skirtach, Sanjay Sinha, Julie De Backer, Jolanda van Hengel
Aantal pagina's: 1 - Liquid marbles : a cost-effective platform to generate cardiospheres from co-cultured cardiomyocytes and cardiac fibroblast for disease modelling(2021)
Auteurs: Jeffrey Aalders, Laurens Léger, Sergio Ledda, Jolanda van Hengel
Aantal pagina's: 1