Onderzoeker
Jan Willem Bek
- Disciplines:Histologie, Musculo-skeletale systemen, Ontwikkelingsbiologie, Biologie van gewervelden, Genetica
Affiliaties
- Vakgroep Biomoleculaire Geneeskunde (Departement)
Lid
Vanaf1 okt 2018 → Heden - Vakgroep Pediatrie en genetica (Departement)
Lid
Vanaf1 jan 2017 → 30 sep 2018
Publicaties
1 - 10 van 10
- Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for Osteogenesis Imperfecta(2023)Volume: 7
Auteurs: Sophie Debaenst, Hanna De Saffel, Jan Willem Bek, Adelbert De Clercq, Tamara Jarayseh, Lauren Sahd, Paul Coucke, Andy Willaert
Aantal pagina's: 1 - Crispant screening in zebrafish as a promising approach for rapid functional screening of osteoporosis candidate genes and known genes for Osteogenesis Imperfecta(2022)
Auteurs: Sophie Debaenst, Hanna De Saffel, Jan Willem Bek, Adelbert De Clercq, Tamara Jarayseh, Lauren Sahd, Paul Coucke, Andy Willaert
Aantal pagina's: 1 - A tapt1 knockout zebrafish line with aberrant lens development and impaired vision models human pediatric cataract(2022)
Auteurs: Tamara Jarayseh, Brecht Guillemyn, Hanna De Saffel, Jan Willem Bek, Sujatha Jagadeesh, Sofie Symoens, Fransiska Malfait, Delfien Syx, Filip Van Nieuwerburgh, Yannick Gansemans, et al.
Aantal pagina's: 1 - RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition(2022)
Auteurs: Carolina de Carvalho Nunes, Lisa Depestel, Liselot Mus, Kaylee M. Keller, Louis Delhaye, Amber Louwagie, Muhammad Rishfi, Alex Whale, Neesha Kara, Simon R. Andrews, et al.
- Lrp5 mutant and crispant zebrafish faithfully model human osteoporosis, establishing the zebrafish as a platform for CRISPR‐based functional screening of osteoporosis candidate genes(2021)
Auteurs: Jan Willem Bek, Chen Shochat, Adelbert De Clercq, Hanna De Saffel, Annekatrien Boel, Juriaan Metz, Frans Rodenburg, David Karasik, Andy Willaert, Paul Coucke
Pagina's: 1749 - 1764 - The zebrafish in biomedical research : a vertebrate model to study skeletal disorders(2021)
Auteurs: Jan Willem Bek
- b3galt6 Knock-out zebrafish recapitulate β3GalT6-deficiency disorders in human and reveal a trisaccharide proteoglycan linkage region(2020)
Auteurs: Sarah Delbaere, Adelbert De Clercq, Shuji Mizumoto, Fredrik Noborn, Jan Willem Bek, Charlotte Gistelinck, Delfien Syx, Phil L. Salmon, Paul Coucke, Göran Larson, et al.
- The zebrafish as a model for recessive types of osteogenesis imperfecta(2019)
Auteurs: Jan Willem Bek, Hanna De Saffel, Osama Essawi, Adelbert De Clercq, Paul Witten, Ann Huysseune, Phil Salmon, Paul Coucke, Andy Willaert
Aantal pagina's: 1 - Beyond the whole-mount phenotype : high-resolution imaging in fluorescence-based applications on zebrafish(2019)
Auteurs: Veronika Oralova, Joana Teixeira Rosa, Mieke Soenens, Jan Willem Bek, Andy Willaert, Paul Witten, Ann Huysseune
- The zebrafish as a model for fragile bone disorders(2019)
Auteurs: Jan Willem Bek, Hanna De Saffel, Osama Essawi, Adelbert De Clercq, Paul Witten, Ann Huysseune, Juriaan Metz, Phil Salmon, Paul Coucke, Andy Willaert
Aantal pagina's: 1