Onderzoeker
Filip Claes
- Disciplines:Proteïnen
Affiliaties
- Switch Laboratorium (VIB-KU Leuven) (Afdeling)
Lid
Vanaf1 apr 2014 → 21 feb 2018 - Dierenfysiologie en Neurobiologie (Afdeling)
Lid
Vanaf16 aug 2010 → 31 mrt 2014 - Centrum voor Moleculaire en Vasculaire Biologie (Afdeling)
Lid
Vanaf15 nov 2003 → 30 sep 2005
Projecten
1 - 2 of 2
- Verbeterde analyse van microRNA-gemedieerde regulatie van signaaltransductie in lymfatische endotheelcellen.Vanaf1 jan 2013 → 31 dec 2013Financiering: FWO Krediet aan Navorser
- Regulatie van lymfangiogenese door specifieke microRNAs.Vanaf1 okt 2011 → 30 sep 2014Financiering: FWO mandaten
Publicaties
1 - 10 van 27
- Reduced Levels of Misfolded and Aggregated Mutant p53 by Proteostatic Activation(2023)
Auteurs: Filip Claes, Rob van der Kant, Mark Fiers, Stein Aerts, Frederic Rousseau, Joost Schymkowitz, Frederik De Smet
- Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein(2023)
Auteurs: Kobe Janssen, Filip Claes, Bert Houben, Mieke Nys, Laleh Khodaparast, Ladan Khodaparast, Nikolaos Louros, Rob van der Kant, Katerina Konstantoulea, Joost Schymkowitz, et al.
- Synthetic Pept-Ins as a Generic Amyloid-Like Aggregation-Based Platform for In Vivo PET Imaging of Intracellular Targets(2021)
Auteurs: Kaat Luyten, Laleh Khodaparast, Ladan Khodaparast, Filip Claes, Rodrigo Gallardo, Michel Koole, Joost Schymkowitz, Guy Bormans, Frederic Rousseau
Pagina's: 2052 - 2064 - Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V(2019)
Auteurs: Filip Claes, Nikolaos Louros, Emiel Michiels, Rob van der Kant, Bert Houben, Wim Robberecht, Frederic Rousseau, Joost Schymkowitz
Pagina's: 443 - 457 - Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis(2018)
Auteurs: Laleh Khodaparast, Ladan Khodaparast, Rodrigo Gallardo, Nikolaos Louros, Emiel Michiels, Reshmi Ramakrishnan, Filip Claes, Mohammad Shahrooei, Abram Aertsen, Sebastien Carpentier, et al.
- Changing Geographic Patterns and Risk Factors for Avian Influenza A(H7N9) Infections in Humans, China(2018)
Auteurs: Jean Artois, Hui Jiang, Xiling Wang, Ying Qin, Morgan Pearcy, Shengjie Lai, Yujing Shi, Juanjuan Zhang, Zhibin Peng, Jiandong Zheng, et al.
Pagina's: 87 - 94 - Could Changes in the Agricultural Landscape of Northeastern China Have Influenced the Long-Distance Transmission of Highly Pathogenic Avian Influenza H5Nx Viruses?(2017)
Auteurs: Marius Gilbert, Diann J Prosser, Geli Zhang, Jean Artois, Madhur S Dhingra, Michael Tildesley, Scott H Newman, Fusheng Guo, Peter Black, Filip Claes, et al.
- Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodeling by p53 aggregation(2017)
Auteurs: Frederik De Smet, Mirian Saiz Rubio, Daphne Hompes, Evelyne Naus, Tobias Langenberg, Bert Houben, Filip Claes, Stéphane Plaisance, Frédéric Amant, Xavier Sagaert, et al.
Pagina's: 24 - 38 - De novo design of a biologically active amyloid(2016)
Auteurs: Rodrigo Gallardo, Frederik De Smet, Filip Claes, Laleh Khodaparast, Ladan Khodaparast, Tobias Langenberg, Maxime Siemons, Manoj Kumar Gautam, Manu Beerens, Aernout Luttun, et al.
- Fibroblast Growth Factor Signaling Affects Vascular Outgrowth and Is Required for the Maintenance of Blood Vessel Integrity(2014)
Auteurs: Frederik De Smet, Filip Claes, Ann Van Schepdael, Mieke Dewerchin, Peter Carmeliet
Pagina's: 1310 - 1317
Patenten
1 - 6 van 6
- Molecules targeting ras protein (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting ras protein (Inventor)