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Onderzoeker
Erik De Clercq
- Disciplines:Microbiologie, Systeembiologie, Laboratoriumgeneeskunde
Affiliaties
- Laboratorium Virologie en Chemotherapie (Rega Instituut) (Afdeling)
Lid
Vanaf1 okt 1999 → 30 sep 2013
Publicaties
41 - 50 van 562
- Discovery of novel biphenyl-substituted pyridone derivatives as potent non-nucleoside reverse transcriptase inhibitors with promising oral bioavailability(2022)
Auteurs: Christophe Pannecouque, Erik De Clercq
- Design, synthesis, and biological evaluation of novel double-winged galloyl derivatives as HIV-1 RNase H inhibitors(2022)
Auteurs: Christophe Pannecouque, Erik De Clercq
- Trends in the disease burden of HBV and HCV infection in China from 1990-2019(2022)
Auteurs: MahmoudReza Pourkarim, Erik De Clercq
Pagina's: 476 - 485 - Design, Synthesis and Structure-Activity Relationships of Phenylalanine-Containing Peptidomimetics as Novel HIV-1 Capsid Binders Based on Ugi Four-Component Reaction(2022)
Auteurs: Erik De Clercq, Christophe Pannecouque
- Towards Efficient and Accurate SARS-CoV-2 Genome Sequence Typing Based on Supervised Learning Approaches(2022)
Auteurs: Erik De Clercq
- Structure-Based design of [(2-Hydroxyethoxy)methyl]-6-(phenylthio)-thymine derivatives as nonnucleoside HIV-1 reverse transcriptase Inhibitors: From HEPTs to Sulfinyl-substituted HEPTs(2022)
Auteurs: Christophe Pannecouque, Erik De Clercq
- Chemical space exploration around indolylarylsulfone scaffold led to a novel class of highly active HIV-1 NNRTIs with spiro structural features(2022)
Auteurs: Erik De Clercq, Christophe Pannecouque
- Expansion of the S-CN-DABO scaffold to exploit the impact on inhibitory activities against the non-nucleoside HIV-1 reverse transcriptase(2022)
Auteurs: Christophe Pannecouque, Erik De Clercq
- Structure-Based Discovery of Novel NH2 -Biphenyl-Diarylpyrimidines as Potent Non-Nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Safety: From NH2-Naphthyl-Diarylpyrimidine to NH2 -Biphenyl-Diarylpyrimidine(2022)
Auteurs: Christophe Pannecouque, Erik De Clercq
Pagina's: 8478 - 8492 - Epidemiology and Clinical Outcomes of HIV Infection in South-Central China: A Retrospective Study From 2003 to 2018(2022)
Auteurs: Erik De Clercq
Patenten
1 - 7 van 7
- Phosphonate nucleosides useful as active ingredients in pharmaceutical compositions for the treatment of viral infections, and intermediates for their production (Inventor)
- 6-[2-(PHOSPHONOMETHOXY)ALKOXY] PYRIMIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY (Inventor)
- Phosphonate nucleosides useful as active ingredients in pharmaceutical compositions for the treatment of viral infections, and intermediates for their production (Inventor)
- Phosponate nucleosides useful as active ingredients in pharmaceutical compositions for the treatment of viral infections, and intermediates for their production (Inventor)
- VIRAL INHIBITORS (Inventor)
- VIRAL INHIBITORS (Inventor)
- PHOSPHONATE NUCLEOSIDES USEFUL AS ACTIVE INGREDIENTS IN PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS, AND INTERMEDIATES FOR THEIR PRODUCTION (Inventor)