Onderzoeker
Annaert Wim
- Disciplines (Flanders Institute for Biotechnology):Analyse van next-generation sequence data, Celdood, Gedragsneurowetenschappen
- Disciplines (KU Leuven):Intracellulaire compartimenten en transport
- Zie ook: Wim Annaert (KU Leuven)
Affiliaties
- Laboratorium voor Membraantransport (VIB-KU Leuven) (Labo)
Verantwoordelijke
Vanaf1 jan 2006 → Heden - Laboratorium voor Membraantransport (VIB-KU Leuven) (Labo)
Lid
Vanaf1 jan 2017 → Heden - Annaert Lab (Onderzoeksgroep)
Verantwoordelijke
Vanaf1 jan 2017 → Heden - Departement Menselijke Erfelijkheid (Departement)
Lid
Vanaf1 okt 1999 → 31 dec 2016
Projecten
1 - 10 of 11
- Presenilin2 in endolysosomal homeostasis: a focus on membrane contact sitesVanaf1 aug 2023 → HedenFinanciering: Andere int. instellingen niet elders genoemd
- Unraveling the role of presenilin1 in organellar calcium homeostasisVanaf1 jan 2023 → HedenFinanciering: Andere int. instellingen niet elders genoemd
- A role for Presenilin 2/?-secretase in endolysosomal homeostasis of human neurons and microglia: relevance to Alzheimer’s diseaseVanaf1 jan 2023 → HedenFinanciering: Privé-financiering van binnenlandse oorsprong - onbepaald
- VIB Grant for Annaert Lab_Period:2022-01-01-2026-12-31Vanaf1 jan 2022 → HedenFinanciering: VOI - Projectmatig onderzoek
- On the role of Presenilins in interorganellar communication and Ca2 + handlingVanaf1 jan 2021 → 31 dec 2023Financiering: Privé-financiering van binnenlandse oorsprong - onbepaald
- The lysosomal exonuclease PLD3 as a late-onset Alzheimer risk factorVanaf1 jun 2020 → 31 mei 2023Financiering: Andere int. instellingen niet elders genoemd
- An integrated in vitro and in vivo study to unravel the function of VPS13C, the first genetic risk factor in Lewy Body diseaseVanaf1 jan 2019 → 31 dec 2020Financiering: Privé-financiering van binnenlandse oorsprong - onbepaald
- New neuronal models for intracellular toxic Aß accumulationVanaf1 jun 2018 → 31 mei 2021Financiering: Andere int. instellingen niet elders genoemd
- Role of ARF6 in PSEN1 mediated endo-lysosomal defectsVanaf1 jan 2018 → 31 dec 2019Financiering: Privé-financiering van binnenlandse oorsprong - onbepaald
- Regulation of Presenilin2-mediated intracellular ab accumulation and effects and lysosomalVanaf1 jan 2017 → 31 dec 2018Financiering: Privé-financiering van binnenlandse oorsprong - onbepaald
Publicaties
1 - 10 van 28
- A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma.(2024)
Auteurs: Joanna Pozniak, Dennis Pedri, Ewout Landeloos, Ada Nowosad, Niccolo Roda, Carlos Ariel Pulido Vicuna, Lotte Pollaris, Ruth Seurinck, Benjamin Rombaut, Frank Vernaillen, et al.
Pagina's: 166-183.e25 - Phospholipase D3 degrades mitochondrial DNA to regulate nucleotide signaling and APP metabolism.(2023)
Auteurs: Zoë Van Acker, Anika Perdok, Katherine North, Ragna Sannerud, Marine Bretou, Willem Annaert
Pagina's: 2847 - Inter-organellar Communication in Parkinson's and Alzheimer's Disease: Looking Beyond Endoplasmic Reticulum-Mitochondria Contact Sites.(2022)
Auteurs: Céline Vrancx, Patrizia Agostinis, Willem Annaert
Pagina's: 900338 - Assembly of gamma-secretase occurs through stable dimers after exit from the endoplasmic reticulum.(2021)
Auteurs: Rosanne Wouters, Ragna Sannerud, Willem Annaert
Pagina's: e201911104 - BNIP3 promotes HIF-1alpha-driven melanoma growth by curbing intracellular iron homeostasis.(2021)
Auteurs: Monica Vara Perez, Matteo Rossi, Maria Livia Sassano, Ana Oliveira, Willem Annaert, Sarah-Maria Fendt, Massimiliano Mazzone, Patrizia Agostinis
Pagina's: e106214 - PIKfyve activity is required for lysosomal trafficking of tau aggregates and tau seeding.(2021)
Auteurs: Alberto Carpinteiro, Andreia Sofia da Costa de Monica Ferreira, Willem Annaert
Pagina's: 100636 - The role of Bcl-2 proteins in modulating neuronal Ca2+ signaling in health and in Alzheimer's disease.(2021)
Auteurs: Willem Annaert
Pagina's: 118997 - ATP13A3 is a major component of the enigmatic mammalian polyamine transport system.(2021)
Auteurs: Ragna Sannerud, Rupert Mayer, Patrizia Agostinis, Willem Annaert, Francis Impens
Pagina's: 100182 - The microglial lysosomal system in Alzheimer's disease: Guardian against proteinopathy.(2021)
Auteurs: Zoë Van Acker, Anika Perdok, Marine Bretou, Willem Annaert
Pagina's: 101444 - The Nanoscopic Organization of Synapse Structures: A Common Basis for Cell Communication.(2021)
Auteurs: Xiaojuan Yang, Willem Annaert
Pagina's: 248
Patenten
1 - 4 van 4
- IMPROVED GAMMA-SECRETASE INHIBITOR SCREENING ASSAYS (Inventor)
- GAMMA-SECRETASE INHIBITOR SCREENING ASSAY (Inventor)
- GAMMA-SECRETASE INHIBITOR SCREENING ASSAY (Inventor)
- GAMMA-SECRETASE INHIBITOR SCREENING ASSAY (Inventor)