Onderzoeker
Aleksandra Siekierska
- Disciplines:Microbiologie, Systeembiologie, Laboratoriumgeneeskunde
Affiliaties
- Laboratorium Virologie en Chemotherapie (Rega Instituut) (Afdeling)
Lid
Vanaf14 mrt 2022 → Heden - Moleculaire Bio-ontdekking (Afdeling)
Lid
Vanaf1 apr 2013 → 13 mrt 2022
Projecten
1 - 1 of 1
- In vivo modellering in zebravis van epileptische encephalopathieën veroorzaakt door mutaties in aminoacyl-tRNA synthetasen.Vanaf1 okt 2015 → 30 sep 2018Financiering: FWO mandaten
Publicaties
11 - 20 van 22
- Methylated flavonoids as anti-seizure agents: Naringenin 4 ',7-dimethyl ether attenuates epileptic seizures in zebrafish and mouse models(2018)
Auteurs: Daniëlle Copmans, Gert Steurs, Yifan Zhang, Annelii Ny, Aleksandra Siekierska, Wim De Borggraeve, Wim Dehaen, Peter de Witte
Pagina's: 124 - 133 - mTOR-related neuropathology in mutant tsc2 zebrafish: Phenotypic, transcriptomic and pharmacological analysis(2017)
Auteurs: Chloë Scheldeman, Aleksandra Siekierska, Daniëlle Copmans, Lieven Lagae, Peter de Witte
Pagina's: 225 - 237 - RECESSIVE VARIANTS IN VARS CAUSE A CLINICAL SYNDROME WITH SEVERE DEVELOPMENTAL DELAY, EPILEPSY AND MICROCEPHALY(2017)
Auteurs: Aleksandra Siekierska, H Stamberger, J Sourbron, T Deconinck, A Kecskes, S Oprescu, Q Waisfisz, K Helbig, K Hardies, D Shinde, et al.
Pagina's: S177 - S177 - Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish(2017)
Auteurs: Yifan Zhang, Michiel Vanmeert, Aleksandra Siekierska, Annelii Ny, Geert Callewaert, Eveline Lescrinier, Wim Dehaen, Peter de Witte
- Automated analysis of brain activity for seizure detection in zebrafish models of epilepsy(2017)
Auteurs: Borbála Hunyadi, Aleksandra Siekierska, Jo Sourbron, Daniëlle Copmans, Peter de Witte
Pagina's: 13 - 24 - Gain-of-function FHF1 mutation causes early-onset epileptic encephalopathy with cerebellar atrophy(2016)
Auteurs: Aleksandra Siekierska, Mala Isrie, Chloë Scheldeman, Niels Vanthillo, Lieven Lagae, Peter de Witte, Hilde Van Esch, Gunnar Buyse
Pagina's: 2162 - 2170 - Structural hot spots for the solubility of globular proteins(2016)
Auteurs: Aleksandra Siekierska, Joost Van Durme, Greet De Baets, Rob van der Kant, Rodrigo Gallardo, Tobias Langenberg, Frederik De Smet, Chris Ulens, Frederic Rousseau, Joost Schymkowitz
Pagina's: 10816 - 10816 - MODELING OF FEVER-ASSOCIATED EPILEPSY SYNDROMES CAUSED BY MUTATIONS IN STX1B IN ZEBRAFISH(2015)
Auteurs: Aleksandra Siekierska, J Schubert, M Langlois, P May, C Huneau, F Becker, H Muhle, Arvid Suls, JR Lemke, CGF De Kovel, et al.
Pagina's: 220 - 220 - DE NOVO LOSS-OF-FUNCTION MUTATIONS IN CHD2 CAUSE A FEVER-SENSITIVE MYOCLONIC EPILEPTIC ENCEPHALOPATHY SHARING FEATURES WITH DRAVET SYNDROME(2014)
Auteurs: A Suls, JJ Jaehn, Angela Kecskés, Y Weber, S Weckhuysen, DC Craiu, Aleksandra Siekierska, T Djemie, Tatiana Afrikanova, P Gormley, et al.
Pagina's: 79 - 80 - Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes(2014)
Auteurs: Aleksandra Siekierska, Angela Kecskés, Peter de Witte, Alex Crawford, Camila Esguerra
Pagina's: 1327 - 1332
Patenten
1 - 2 van 2