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Onderzoeker
Abhi Singh
- Disciplines:Virologie
Affiliaties
- Laboratorium Virologie en Chemotherapie (Rega Instituut) (Afdeling)
Lid
Vanaf27 sep 2018 → Heden
Projecten
1 - 2 of 2
- Combinatie van nsp12 en nsp15 remmers: een krachtig concept voor onderdrukking van coronavirus replicatie en transcriptieVanaf1 okt 2022 → HedenFinanciering: IOF - technologie concept exploratie
- Structuur-gebaseerde medicijnontwikkeling tegen het Nipah-virus RNA polymeraseVanaf1 okt 2022 → HedenFinanciering: Eigen Middelen zoals patrimonium, inschrijvingsgelden, giften, ....
Publicaties
1 - 10 van 11
- Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine(2022)
Auteurs: Abhi Singh, Dominique Schols, Piet Herdewyn, Christophe Pannecouque, Kalyan Das
- Insights into HIV-1 Reverse Transcriptase (RT) Inhibition and Drug Resistance from Thirty Years of Structural Studies(2022)
Auteurs: Abhi Singh, Kalyan Das
- Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - targeting P-pocket by fragment screening(2021)
Auteurs: Abhi Singh, Kalyan Das
- Exploring the dNTP -binding site of HIV-1 reverse transcriptase for inhibitor design(2021)
Auteurs: Weijie Gu, Sergio Martinez, Abhi Singh, Jef Rozenski, Dominique Schols, Piet Herdewyn, Kalyan Das, Steven De Jonghe
- Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - targeting P-pocket by fragment screening.(2021)
Auteurs: Abhi Singh, Kalyan Das
Pagina's: 7127 - Talin rod domain-containing protein 1 (TLNRD1) is a novel actin-bundling protein which promotes filopodia formation(2021)
Auteurs: Abhi Singh
- Development of a Novel SPR Assay to Study CXCR4-Ligand Interactions(2020)
Auteurs: Arnaud Boonen, Abhi Singh, Kalyan Das, Tom Van Loy, Sam Noppen, Dominique Schols
- Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds(2020)
Auteurs: Abhi Singh
Pagina's: 3485 - 3507 - Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2)(2019)
Auteurs: Abhi Singh
Pagina's: 4013 - 4029 - Structure and N-acetylglucosamine binding of the distal domain of mouse adenovirus 2 fibre(2018)
Auteurs: Abhi Singh, Thanh H Nguyen, Marton Z Vidovszky, Balazs Harrach, Maria Benko, Alan Kirwan, Lokesh Joshi, Michelle Kilcoyne, M Alvaro Berbis, F Javier Canada, et al.
Pagina's: 1494 - 1508