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Octrooi

Halogenated benzotropolones as ATG4B inhibitors

The present invention relates to compounds having a benzotropolone core, and compositions containing said compounds acting as ATG4B inhibitors, thereby inhibiting autophagy. Moreover, the present invention provides processes for the preparation of the disclosed compounds, as well as methods of using them, for instance as a medicine, in particular for the treatment of cell proliferative disorders, such as cancer.
Octrooi-publicatienummer: US10738002
Jaar aanvraag: 2020
Jaar toekenning: 2020
Jaar van publicatie: 2020
Status: Toegewezen
Technologiedomeinen: Organische fijne chemie, Farmaceutische producten
Gevalideerd voor IOF-sleutel: Ja
Toegewezen aan: Associatie Universiteit & Hogescholen Antwerpen