< Terug naar vorige pagina

Octrooi

Detecting and treating dementia

This document relates to methods and materials for detecting mutations that can be linked to dementia. For example, methods and materials for detecting one or more mutations within PGRN nucleic acid are provided. This document also provides methods and materials for detecting the level of progranulin expression. In addition, this document relates to methods and materials for treating mammals having a neurodegenerative disorder (e.g., dementia). For example, methods and materials for increasing PGRN polypeptide levels in mammals are provided, as are methods and materials for identifying agents that can be used to increase PGRN polypeptide levels in mammals.
Octrooi-publicatienummer: US9486541
Jaar aanvraag: 2013
Jaar toekenning: 2016
Jaar van publicatie: 2016
Status: Toegewezen
Technologiedomeinen: Farmaceutische producten
Gevalideerd voor IOF-sleutel: Ja
Toegewezen aan: Associatie Universiteit & Hogescholen Antwerpen