Antifungal 5,6-dihydro-4-[(difluoroethyl)phenyl]-4H-pyrrolo[1,2-?][1,4]benzodiazepine and 4-(difluoroethyl)phenyl-6H-pyrrolo[1,2-?][1,4]benzodiazepine derivatives

The present invention concerns novel compounds of Formula (I): wherein R1, R2, R3, R4, R5 and R6 have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.

Octrooi-publicatienummer: US9637490

Jaar aanvraag: 2011

Jaar toekenning: 2017

Jaar van publicatie: 2017

Status: Toegewezen

Technologiedomeinen: Farmaceutische producten

Gevalideerd voor IOF-sleutel: Ja

Toegewezen aan: Associatie Universiteit & Hogescholen Antwerpen