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Octrooi

Devices and methods for three-dimensional growth of cells

The invention relates to devices for the culture of cellular aggregates comprising a three-dimensional network of interconnected vessels of a biocompatible liquid- and gas-permeable photo polymerised material, wherein the three-dimensional network is connected to a plurality of inlets and a plurality of outlets for the delivery of liquids, and overlayed with a secondary hydrogel network wherein the cellular aggregates are embedded. Herein defined vessels within the three-dimensional network are blocked, thereby defining at least one spatially segregated network within and structurally in contact with the three-dimensional network, wherein the at least one spatially segregated network is connected to a separate inlet and a separate outlet, allowing the supply of a liquid to a subregion within the three-dimensional network.
Octrooi-publicatienummer: WO2019149752
Jaar aanvraag: 2019
Jaar toekenning: 2020
Jaar van publicatie: 2019
Status: Aangevraagd
Technologiedomeinen: Biotechnologie
Gevalideerd voor IOF-sleutel: Ja
Toegewezen aan: Associatie KULeuven