BACE1 inhibitory antibodies

The present invention relates to antibodies with a specificity for BACE1. More specifically, the invention provides monoclonal antibodies that bind to BACE1 and are capable of inhibiting the activity of BACE1 and methods producing these antibodies. The antibodies can be used for research and medical applications. Specific applications include the use of BACE1-specific antibodies for the treatment of Alzheimer's disease.

Octrooi-publicatienummer: US8956614

Jaar aanvraag: 2010

Jaar toekenning: 2015

Jaar van publicatie: 2015

Status: Toegewezen

Technologiedomeinen: Meting, Analyse van biologische materialen, Farmaceutische producten

Gevalideerd voor IOF-sleutel: Ja

Toegewezen aan: Associatie KULeuven