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Octrooi
SCREENING METHODS FOR COMPOUNDS THAT MODULATE ARF-6 MEDIATED ENDOSOMAL REDISTRIBUTION
The invention relates to the field of disorders of the peripheral or central nervous system, in particular, Alzheimer's disease, and the prevention and/or treatment thereof. In particular, the invention relates to ARF6 and/or ARF6 effector proteins as new targets in Alzheimer's disease, and based thereon, screening methods for compounds that reduce amyloid beta peptide formation in mammalian cells by affecting ARF6-mediated endosomal sorting.
Octrooi-publicatienummer: US8790887
Jaar aanvraag: 2010
Jaar toekenning: 2014
Jaar van publicatie: 2014
Status: Toegewezen
URI: link to Espacenet
Technologiedomeinen: Farmaceutische producten
Gevalideerd voor IOF-sleutel: Ja
Toegewezen aan: Associatie KULeuven