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Publicatie
Signaling is silver, silence is golden: RHBDL2 intramembrane proteolysis prevents stochastic Ca2+ signaling in unstimulated cells
Tijdschriftbijdrage - Tijdschrift Editorial
In this issue of Molecular Cell, Grieve et al. (2021) reveal Orai1/CRAC channels as atypical substrates of the RHBDL2 rhomboid and unveil the selective processing of stochastically activated CRAC channels by RHBLD2 as the "conformational surveillance" mechanism that prevents unwanted CRAC signaling in unstimulated cells.
Tijdschrift: Molecular Cell
ISSN: 1097-2765
Issue: 23
Volume: 81
Pagina's: 4763 - 4765
Jaar van publicatie:2021
Toegankelijkheid:Open