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Publicatie

Electromagnetic Field as a Treatment for Cerebral Ischemic Stroke

Tijdschriftbijdrage - Review Artikel

Cerebral stroke is a leading cause of death and adult-acquired disability worldwide. To this date, treatment options are limited; hence, the search for new therapeutic approaches continues. Electromagnetic fields (EMFs) affect a wide variety of biological processes and accumulating evidence shows their potential as a treatment for ischemic stroke. Based on their characteristics, they can be divided into stationary, pulsed, and sinusoidal EMF. The aim of this review is to provide an extensive literature overview ranging from in vitro to even clinical studies within the field of ischemic stroke of all EMF types. A thorough comparison between EMF types and their effects is provided, as well as an overview of the signal pathways activated in cell types relevant for ischemic stroke such as neurons, microglia, astrocytes, and endothelial cells. We also discuss which steps have to be taken to improve their therapeutic efficacy in the frame of the clinical translation of this promising therapy.

Tijdschrift: Frontiers in Molecular Biosciences
ISSN: 2296-889X
Volume: 8
Jaar van publicatie:2021
Trefwoorden:stroke, cerebral ischemia, electromagnetic field, neuroprotection, neurorehabilitation, pulsed electromagnetic field, sinusoidal
BOF-keylabel:ja
IOF-keylabel:ja
BOF-publication weight:2
Auteurs:International
Authors from:Higher Education
Toegankelijkheid:Open