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Palladium-catalyzed post-Ugi arylative dearomatization/Michael addition cascade towards plicamine analogues

Tijdschriftbijdrage - Tijdschriftartikel

A palladium-catalyzed intramolecular cyclization of Ugi-adducts via a cascade dearomatization/aza-Michael addition process has been developed. Diverse plicamine analogues are constructed in a rapid, highly efficient and step-economical manner, through the combination of an Ugi-4CR and a palladium-catalyzed dearomatization. The synthetic utility of this approach is illustrated by further functional group transformations.
Tijdschrift: Organic & Biomolecular Chemistry
ISSN: 1477-0520
Issue: 44
Volume: 19
Pagina's: 9752 - 9757
Jaar van publicatie:2021
BOF-keylabel:ja
IOF-keylabel:ja
BOF-publication weight:1
CSS-citation score:1
Auteurs:International
Authors from:Higher Education
Toegankelijkheid:Open