A Multicomponent Approach toward Angularly Fused/Linear Bitriazoles: A Cascade Cornforth Rearrangement and Triazolization

A multicomponent reaction of triazoloketones, primary amines, and 4-nitrophenyl azide was developed for the synthesis of hitherto unknown angularly fused/linear bitriazoles. The two-stage mechanism was well proven by the isolation of the intermediate. This sequential reaction consists of Cornforth rearrangement and triazolization, which has also been demonstrated in a one-pot manner.

Jaar van publicatie:2021

BOF-keylabel:ja

IOF-keylabel:ja

BOF-publication weight:2

CSS-citation score:1

Authors from:Higher Education

Toegankelijkheid:Open