A novel view on GPCR research and drug discovery using cell-based electrical impedance

We have developed such an advanced multisine EIS system with a superior signal to noise ratio that is able to generate high content multidimensional EIS data. This system has already proven to be applicable to study cytotoxicity and is able to distinguish between different types of cell death in a fast and non-invasive manner. The goal of this PhD project is to expand this system to the study of disease-relevant receptor signaling by demonstrating its robustness, efficacy, and applicability to many aspects of receptor research.

Jaar van publicatie:2020

Toegankelijkheid:Open