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Ethyl acetate as solvent for the synthesis of poly(2-ethyl-2-oxazoline)

Tijdschriftbijdrage - Tijdschriftartikel

Poly(2-ethyl-2-oxazoline) (PEtOx) is the most common poly(2-oxazoline) for biomedical applications resulting from its high water-solubility, good commercial availability and well-controlled polymerization. In this article, we report the polymerization of 2-ethyl-2-oxazoline (EtOx) in ethyl acetate to replace the current state-of-the-art polymerization of EtOx in acetonitrile and chlorobenzene. This switch towards ethyl acetate as green solvent is an important improvement towards pharmaceutical compliance/compatibility, besides the lower burden for the environment.
Tijdschrift: GREEN CHEMISTRY
ISSN: 1463-9262
Issue: 5
Volume: 22
Pagina's: 1747 - 1753
Jaar van publicatie:2020
BOF-keylabel:ja
IOF-keylabel:ja
BOF-publication weight:3
CSS-citation score:2
Authors from:Higher Education
Toegankelijkheid:Closed