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Neonatal follow-up of 995 consecutively born children after embryo biopsy for PGD

Tijdschriftbijdrage - Tijdschriftartikel

BACKGROUND: Outcome data on children born after assisted reproduction treatments are important for both patients and health-care providers. The objective of this study was to determine whether embryo biopsy as performed in PGD has an impact on the health of infants up to 2 months of age.

METHODS: A prospective comparative follow-up study of children born after PGD and children born after ICSI by collecting written reports and performing a physical examination at 2 months was performed. Auxological data at birth and physical findings up to 2 months of age were compared for 995 children consecutively live born after embryo biopsy (1994-2009) and for a control group of 1507 children born after ICSI with embryo transfer on Day 5.

RESULTS: No differences regarding mean term, prematurity (term
CONCLUSIONS: Embryo biopsy for PGD does not introduce extra risk to the overall medical condition of newborn children. Multiples born following embryo biopsy appear to be at lower risk for low birthweight compared with multiples born following ICSI.
Tijdschrift: Hum Reprod
ISSN: 0268-1161
Volume: 1
Pagina's: 288-293
Jaar van publicatie:2012
Trefwoorden:embryo biopsy, birth weight, ICSI, PGD, neonatal follow-up
  • ORCID: /0000-0002-1805-9962/work/62884817
  • ORCID: /0000-0001-8092-3304/work/62062537
  • ORCID: /0000-0001-7861-9426/work/61773007
  • Scopus Id: 83755224743