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Publicatie
Proton-pump inhibitor omeprazole attenuates hyperoxia induced lung injury
Tijdschriftbijdrage - Tijdschriftartikel
The administration of supplemental oxygen to treat ventilatory insufficiency may lead to the formation of reactive oxygen species and subsequent tissue damage. Cytochrome P4501A1 (CYP1A1) can modulate hyperoxic lung injury by a currently unknown mechanism. Our objective was to evaluate the effect of administration of omeprazole on the induction of CYP1A1 and its influence on hyperoxic lung injury in an established preterm rabbit model.
Tijdschrift: Journal of Translational Medicine
ISSN: 1479-5876
Issue: 1
Volume: 14
Pagina's: 247
Jaar van publicatie:2016
BOF-keylabel:ja
IOF-keylabel:ja
BOF-publication weight:1
CSS-citation score:1
Auteurs:International
Authors from:Higher Education
Toegankelijkheid:Open