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Cortisol metabolism in critical illness: implications for clinical care

Tijdschriftbijdrage - Tijdschriftartikel

Critical illness is uniformly characterized by elevated plasma cortisol concentrations, traditionally attributed exclusively to increased cortisol production driven by an activated hypothalamic pituitary adrenal axis. However, as plasma adrenocorticotropic hormone (ACTH) concentrations are often not elevated or even low during critical illness, alternative mechanisms must contribute.
Tijdschrift: Current Opinion in Endocrinology Diabetes and Obesity
ISSN: 1752-296X
Issue: 3
Volume: 21
Pagina's: 185 - 92
Jaar van publicatie:2014
BOF-keylabel:ja
IOF-keylabel:ja
BOF-publication weight:1
CSS-citation score:1
Authors from:Higher Education
Toegankelijkheid:Closed