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Reduced cortisol metabolism during critical illness

Tijdschriftbijdrage - Tijdschriftartikel

Critical illness is often accompanied by hypercortisolemia, which has been attributed to stress-induced activation of the hypothalamic-pituitary-adrenal axis. However, low corticotropin levels have also been reported in critically ill patients, which may be due to reduced cortisol metabolism.
Tijdschrift: New England Journal of Medicine
ISSN: 0028-4793
Issue: 16
Volume: 368
Pagina's: 1477 - 1488
Jaar van publicatie:2013
BOF-keylabel:ja
IOF-keylabel:ja
BOF-publication weight:10
CSS-citation score:3
Auteurs:International
Authors from:Hospital, Higher Education
Toegankelijkheid:Open