Onderzoeker
Els Pardon
- Trefwoorden (Vrije Universiteit Brussel):Toegepaste biologische wetenschappen
- Disciplines (Flanders Institute for Biotechnology):(Bio)moleculaire modellering en design, Analytische biochemie, Medische biofysica
- Zie ook: Els Pardon (Vlaams Instituut voor Biotechnologie)
Affiliaties
- Structurele Biologie Brussel (Onderzoeksgroep)
Lid
Vanaf1 jan 1998 → Heden - Toegepaste Biologische Wetenschappen (Departement)
Lid
Vanaf8 apr 2019 → Heden - Steyaert Lab (Onderzoeksgroep)
Lid
Vanaf1 jan 2017 → Heden - Cellulaire en Moleculaire Immunologie (Onderzoeksgroep)
Lid
Vanaf1 feb 2003 → 31 dec 2006 - Toegepaste Biologische Wetenschappen (Departement)
Lid
Vanaf1 jan 1999 → 20 okt 2022 - Ultrastructuur (Onderzoeksgroep)
Lid
Vanaf1 jul 1998 → 1 jan 2010
Publicaties
1 - 10 van 108
- Crystal structure of human serum albumin in complex with megabody reveals unique human and murine cross-reactive binding site(2024)
Auteurs: Sofia De Felice, Zhanna Romanyuk, Monica Chinellato, Giulia Zoia, Sara Linciano, Yoichi Kumada, Els Pardon, Jan Steyaert, Alessandro Angelini, Laura Cendron
- Structure and function of the EA1 surface layer of Bacillus anthracis(2023)
Auteurs: Adrià Sogues, Antonella Fioravanti, Wim Jonckheere, Els Pardon, Jan Steyaert, Han Remaut
- Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies(2023)
Auteurs: Rossitza N Irobalieva, Ioannis Manolaridis, Scott M Jackson, Dongchun Ni, Els Pardon, Henning Stahlberg, Jan Steyaert, Kaspar P Locher
- Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition(2023)
Auteurs: Vadim Kotov, Maxime Killer, Katharina E J Jungnickel, Tao Jian-feng Chen Lei, Giada Finocchio, Josi Steinke, Kim Bartels, Jan Strauss, Florine Dupeux, Anne-Sophie Humm, et al.
- In vivo and in vitro characterizations of melibiose permease (MelB) conformation-dependent nanobodies reveal sugar-binding mechanisms(2023)
Auteurs: Satoshi Katsube, Katleen Willibal, Sangama Vemulapally, Parameswaran Hariharan, Elena B. Tikhonova, Els Pardon, H Ronald Kaback, Jan Steyaert, Lan Guan
- Bypassing the Need for Cell Permeabilization(2023)
Auteurs: A Breine, K Van Holsbeeck, C Martin, S Gonzalez, M Mannes, Els Pardon, Jan Steyaert, Han Remaut, Steven Ballet, C Van der Henst
Pagina's: 1234-1243 - Structural basis of purine nucleotide inhibition of human uncoupling protein 1(2023)
Auteurs: Scott A. Jones, Prerana Gogoi, Jonathan J Ruprecht, Martin S King, Yang Lee, Thomas Zögg, Els Pardon, Deepak Chand, Stefan Steimle, Danielle M. Copeman, et al.
- Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils(2023)
Auteurs: Romany Abskharon, Hope Pan, Michael R Sawaya, Paul M Seidler, Eileen J Olivares, Yu-Heng Chen, Kevin A Murray, Jeffrey Zhang, Carter Lantz, Megan Bentzel, et al.
- Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway(2022)
Auteurs: Lorenzo Maso, Filippo Vascon, Monica Chinellato, Frédéric Goormaghtigh, Pierangelo Bellio, Enrica Campagnaro, Laurence Van Melderen, Maria Ruzzene, Els Pardon, Alessandro Angelini, et al.
Pagina's: 1479-1493.e9 - Structural basis of sodium-dependent bile salt uptake into the liver(2022)
Auteurs: Kapil Goutam, Francesco Ielasi, Els Pardon, Jan Steyaert, Nicolas Reyes
Pagina's: 1015-1020
Patenten
1 - 10 van 10
- Cystic fibrosis transmembrane conductance regulator stabilizing agents (Inventor)
- Positive allosteric modulators of the calcium-sensing receptor (Inventor)
- Epitope tag for affinity-based applications (Inventor)
- Binding domains directed against gpcr: g protein complexes and uses derived thereof (Inventor)
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof (Inventor)
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof (Inventor)
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof (Inventor)
- Muscarinic acetylcholine receptor binding agents and uses thereof (Inventor)
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof (Inventor)
- Means and methods for selection of specific binders (Inventor)