Onderzoeker
Adriaan Verhelle
- Disciplines:Medische systeembiologie, Medische biochemie en metabolisme, Laboratoriumgeneeskunde, Medicinale chemie, Biochemie en metabolisme
Affiliaties
- Vakgroep Biochemie (Departement)
Lid
Vanaf1 jan 2013 → 24 sep 2017
Publicaties
1 - 10 van 11
- Nanobodies targeting cortactin proline rich, helical and actin binding regions downregulate invadopodium formation and matrix degradation in SCC-61 cancer cells(2018)
Auteurs: Laurence Bertier, Tim Hebbrecht, Elien Mettepenningen, Natasja De Wit, Adriaan Verhelle, Jan Gettemans
Pagina's: 230 - 241 - AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model(2017)
Auteurs: Adriaan Verhelle, Nair Nisha, Inge Everaert, Wouter Van Overbeke, Lynn Supply, Cindy Peleman, Tony Lahoutte, Nick Devoogdt, Wim Derave, Chuah K Marinee, et al.
Pagina's: 1353 - 1364 - Gelsolin amyloidosis : a diagnostic and therapeutic nanobody approach(2017)
Auteurs: Adriaan Verhelle
- Non-invasive imaging of amyloid deposits in a mouse model of AGel using 99mTc-modified nanobodies and SPECT/CT(2016)
Auteurs: Adriaan Verhelle, Wouter Van Overbeke, Cindy Peleman, Rebecca De Smet, Tony Lahoutte, Nick Devoogdt, Jan Gettemans
Pagina's: 887 - 897 - An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model(2015)
Auteurs: Wouter Van Overbeke, Jantana Wongsantichon, Inge Everaert, Adriaan Verhelle, Anantasak Loonchanta, Leslie D Burtnick, Ariane De Ganck, Tino Hochepied, Jody Haigh, Claude Cuvelier, et al.
Pagina's: 2492 - 2507 - A nanobody modulates the p53 transcriptional program without perturbing its functional architecture(2014)
Auteurs: Jonas Bethuyne, Steven De Gieter, Abel Garcia-Pino, Adriaan Verhelle, Gholamreza Hassanzadeh-Ghassabeh, Remy Loris, Jan Gettemans
Pagina's: 12928 - 12938 - Chaperone nanobodies protect gelsolin against MT1-MMP degradation and alleviate amyloid burden in the gelsolin amyloidosis mouse model(2014)
Auteurs: Wouter Van Overbeke, Adriaan Verhelle, Inge Everaert, Joël Vandekerckhove, Claude Cuvelier, Wim Derave, Jan Gettemans
Pagina's: 1768 - 1778 - A nanobody‐based approach to amyloid diseases, the gelsolin case study
Auteurs: Adriaan Verhelle, Jan Gettemans, Ana-Maria Fernandez-Escamilla
Pagina's: 313 - 335 - A new survivin tracer tracks, delocalizes and captures endogenous survivin at different subcellular locations and in distinct organelles
Auteurs: Els Beghein, Isabel Van Audenhove, Adriaan Verhelle, Ariane De Ganck, Jan Gettemans
- VCA nanobodies target N-WASp to reduce invadopodium formation and functioning
Auteurs: Tim Hebbrecht, Isabel Van Audenhove, Adriaan Verhelle, Jan Gettemans