Onderzoeker
Simon Van Herck
- Trefwoorden:immunotherapie, immunomodulatie, STING, Nanomedicijen
- Disciplines:Toegepaste immunologie, Particle design en -technologie, Kankertherapie, Biofarmaceutica, Nanochemie
Affiliaties
- Vakgroep Geneesmiddelenleer (Departement)
Lid
Vanaf24 nov 2014 → Heden
Projecten
1 - 2 of 2
- Normaliseren tumor pH de angel weer antitumorimmuniteit brengenVanaf1 okt 2021 → HedenFinanciering: FWO junior postdoctoraal mandaat
- PRECISIE IMMUNO-CONSTRUCTIE VAN DE TUMOR MICROOMGEVINGVanaf1 okt 2019 → 30 sep 2021Financiering: BOF - postdoctorale mandaten
Publicaties
1 - 10 van 28
- Lipid nanoparticle delivery alters the adjuvanticity of the TLR9 agonist CpG by innate immune activation in lymphoid tissue(2023)
Auteurs: Zifu Zhong, Yong Chen, Kim Deswarte, Heleen Lauwers, Emily De Lombaerde, Xiaole Cui, Simon Van Herck, Tingting Ye, Mark Gontsarik, Stefan Lienenklaus, et al.
- Smart hydrogels delivered by high pressure aerosolization can prevent peritoneal adhesions(2023)
Auteurs: Helena Braet, Peter-Paul Fransen, Yong Chen, Simon Van Herck, Remco Mariën, Valérie Vanhoorne, Wim Ceelen, Annemieke Madder, Steven Ballet, Richard Hoogenboom, et al.
Pagina's: 138 - 150 - In situ tumor vaccination with calcium‐linked degradable coacervate nanocomplex co‐delivering photosensitizer and TLR7/8 agonist to trigger effective anti‐tumor immune responses(2022)
Auteurs: Yutong Liu, Hui Li, Huajun Zhao, Yanyun Hao, Simon Van Herck, Zejun Xu, Guan Wang, Xiao Wang, Xinke Zhang, Xiaoyan Ge, et al.
- Sterilizing immunity against SARSU+2010CoVU+20102 infection in mice by a singleU+2010shot and lipid amphiphile imidazoquinoline TLR7/8 agonistU+2010adjuvanted recombinant spike protein vaccine**(2021)
Auteurs: Sonia Jangra, Jana De Vrieze, Angela Choi, Raveen Rathnasinghe, Gabriel Laghlali, Annemiek Uvyn, Simon Van Herck, Lutz Nuhn, Kim Deswarte, Niek Sanders, et al.
Pagina's: 9467 - 9473 - Lipid nature and alkyl length influence lymph node accumulation of lipid-polyethylene glycol amphiphiles(2021)
Auteurs: Jana De Vrieze, Antonio Pires da Silva Baptista, Lutz Nuhn, Simon Van Herck, Kim Deswarte, Haijun Yu, Bart Lambrecht, Bruno De Geest
- Lipid-polyglutamate nanoparticle vaccine platform(2021)
Auteurs: Dorien Van Lysebetten, Alessio Malfanti, Kim Deswarte, Kaloian Koynov, Bianka Golba, Tingting Ye, Sabah Kasmi, Alexander Lamoot, Yong Chen, Simon Van Herck, et al.
Pagina's: 6011 - 6022 - Potent and prolonged innate immune activation by enzyme-responsive imidazoquinoline TLR7/8 agonist prodrug vesicles(2020)
Auteurs: Bi Wang, Simon Van Herck, Yong Chen, Xiangyang Bai, Kim Deswarte, Niek Sanders, Stefan Lienenklaus, Hans W. Scheeren, Sunil A. David, Fabian Kiessling, et al.
Pagina's: 12133 - 12139 - Design of pH-degradable polymer-lipid amphiphiles using a ketal-functionalized RAFT chain transfer agent(2020)
Auteurs: Jana De Vrieze, Simon Van Herck, Lutz Nuhn, Bruno De Geest
- Imidazoquinoline-conjugated degradable coacervate conjugate for local cancer immunotherapy(2020)
Auteurs: Hui Li, Simon Van Herck, Yongjun Liu, Yanyun Hao, Xiaochu Ding, Lutz Nuhn, Francis Combes, Niek Sanders, Stefan Lienenklaus, Stefaan De Koker, et al.
Pagina's: 4993 - 5000 - Zebrafish embryos allow prediction of nanoparticle circulation times in mice and facilitate quantification of nanoparticle-cell interactions(2020)
Auteurs: Nils-Jorgen Knudsen Dal, Agnese Kocere, Jens Wohlmann, Simon Van Herck, Tobias A. Bauer, Julien Resseguier, Shahla Bagherifam, Hilde Hyldmo, Matthias Barz, Bruno De Geest, et al.