Onderzoeker
Yehudi Bloch
- Disciplines (Flanders Institute for Biotechnology):Analyse van next-generation sequence data, Adaptieve immunologie, Bacteriologie
- Disciplines (Ghent University):Biofysica, Moleculaire en celbiologie, Medische biochemie en metabolisme, Laboratoriumgeneeskunde, Microbiologie, Systeembiologie, Plantenbiologie, Biochemie en metabolisme, Medicinale en biomoleculaire chemie
Affiliaties
- Vakgroep Biomedische Moleculaire Biologie (Departement)
Lid
Vanaf1 okt 2022 → 31 dec 2022 - Savvides Lab (Onderzoeksgroep)
Lid
Vanaf1 jan 2017 → 31 dec 2022 - Vakgroep Biochemie en Microbiologie (Departement)
Lid
Vanaf1 jan 2012 → 30 sep 2022
Projecten
1 - 2 of 2
- Opheldering van de structurele en moleculaire basis van de pruritogene Interleukine-31 gemedieerde signalerende complexen.Vanaf1 okt 2018 → 30 sep 2022Financiering: FWO mandaten
- Structurele inzichten in de assemblage van de inflammatoire IL-23 signalering complexenVanaf1 jan 2013 → 31 dec 2016Financiering: IWT persoonsgebonden financ. - specialisatiebeurzen
Publicaties
1 - 10 van 15
- Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding(2022)
Auteurs: Steven Timmermans, Nicolette J.D. Verhoog, Kelly Van Looveren, Sylviane Dewaele, Tino Hochepied, Melanie Eggermont, Barbara Gilbert, Anne Boerema-de Munck, Tineke Vanderhaeghen, Joke Vanden Berghe, et al.
- Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27(2022)
Auteurs: Katarzyna Skladanowska, Yehudi Bloch, Jamie Strand, Kerry F. White, Jing Hua, Daniel Aldridge, Martin Welin, Derek T. Logan, Arne Soete, Romain Merceron, et al.
- Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity(2022)
Auteurs: Sammy Detry, Julie Andries, Yehudi Bloch, Cem Gabay, Danielle Clancy, Savvas Savvides
- Structural basis of cytokine-mediated activation of ALK family receptors(2021)
Auteurs: Steven De Munck, Mathias Provost, Michiko Kurikawa, Ikuko Omori, Junko Mukohyama, Jan Félix, Yehudi Bloch, Omar Abdel-Wahab, J. Fernando Bazan, Akihide Yoshimi, et al.
Pagina's: 143 - 147 - Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis(2020)
Auteurs: Sandra Kozak, Yehudi Bloch, Steven De Munck, Aleksandra Mikula, Isabel Bento, Savvas Savvides, Rob Meijers
Pagina's: 1244 - 1255 - Pathophysiology and inhibition of IL-23 signaling in psoriatic arthritis : a molecular insight(2019)
Auteurs: Cuong Thach Nguyen, Yehudi Bloch, Savvas Savvides, Iannis E Adamopoulos
Pagina's: 15 - 22 - Revisiting the combinatorial potential of cytokine subunits in the IL-12 family(2019)
Auteurs: Sammy Detry, Marnik Vuylsteke, Savvas Savvides, Yehudi Bloch
Pagina's: 240 - 248 - Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle(2019)
Auteurs: Koen Verschueren, Clement Blanchet, Jan Felix, Dirk De Vos, Yehudi Bloch, Jozef Van Beeumen, Dmitri Svergun, Irina Gutsche, Savvas Savvides, Kenneth Verstraete
Pagina's: 571 - 575 - Structure, mechanism and antagonism of the pro-inflammatory receptor complex mediated by interleukin-23(2018)
Auteurs: Yehudi Bloch
- Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha(2018)
Auteurs: Renée Van der Cruyssen, Eveline Verheugen, Sofie Van Gassen, Yvan Saeys, Takao Iwawaki, Yehudi Bloch, Savvas Savvides, Michael Drennan