Onderzoeker
Wouter Van Overbeke
- Disciplines:Medische systeembiologie, Medische biochemie en metabolisme, Laboratoriumgeneeskunde, Medicinale chemie, Biochemie en metabolisme
Affiliaties
- Vakgroep Biochemie (Departement)
Lid
Vanaf1 okt 2009 → 20 sep 2015
Projecten
1 - 1 of 1
- Gelsoline enkel-keten antilichamen (nanobodies) als therapeuticum en onderzoeksinstrument in de monogene aandoening FAF (familial Amyloidosis of the Finnish type).Vanaf1 okt 2009 → 26 feb 2015Financiering: IWT persoonsgebonden financ. - specialisatiebeurzen
Publicaties
1 - 6 van 6
- AAV9 delivered bispecific nanobody attenuates amyloid burden in the gelsolin amyloidosis mouse model(2017)
Auteurs: Adriaan Verhelle, Nair Nisha, Inge Everaert, Wouter Van Overbeke, Lynn Supply, Cindy Peleman, Tony Lahoutte, Nick Devoogdt, Wim Derave, Chuah K Marinee, et al.
Pagina's: 1353 - 1364 - Non-invasive imaging of amyloid deposits in a mouse model of AGel using 99mTc-modified nanobodies and SPECT/CT(2016)
Auteurs: Adriaan Verhelle, Wouter Van Overbeke, Cindy Peleman, Rebecca De Smet, Tony Lahoutte, Nick Devoogdt, Jan Gettemans
Pagina's: 887 - 897 - Keeping mutant plasma gelsolin safe from harm: gelsolin nanobodies act as a chaperone against pathological proteolysis(2015)
Auteurs: Wouter Van Overbeke
- An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model(2015)
Auteurs: Wouter Van Overbeke, Jantana Wongsantichon, Inge Everaert, Adriaan Verhelle, Anantasak Loonchanta, Leslie D Burtnick, Ariane De Ganck, Tino Hochepied, Jody Haigh, Claude Cuvelier, et al.
Pagina's: 2492 - 2507 - Chaperone nanobodies protect gelsolin against MT1-MMP degradation and alleviate amyloid burden in the gelsolin amyloidosis mouse model(2014)
Auteurs: Wouter Van Overbeke, Adriaan Verhelle, Inge Everaert, Joël Vandekerckhove, Claude Cuvelier, Wim Derave, Jan Gettemans
Pagina's: 1768 - 1778 - Camelid single-domain antibodies as a therapeutic approach for familial amyloidosis of the Finnish type (FAF)(2010)Volume: 17
Auteurs: Wouter Van Overbeke, M Guaraldo, Joël Vandekerckhove, Ariane De Ganck, Jan Gettemans
Pagina's: 97 - 97