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Octrooi

THERAPEUTIC NANOPARTICLES AND METHODS OF USE THEREOF

The present invention relates to a method and composition for optimized intracellular delivery of nucleic acids, in particular mRNA. In addition to mRNA, the composition, in particular a nanoparticle, may include a glycolipid antigen. Combinations with checkpoint inhibitors are also provided. The method and composition of the invention targets antigen presenting cells and is especially useful for immunotherapy and vaccination purposes.
Octrooi-publicatienummer: EP3852727
Jaar aanvraag: 2021
Jaar toekenning: 2022
Jaar van publicatie: 2021
Status: Aangevraagd
Technologiedomeinen: Farmaceutische producten
Gevalideerd voor IOF-sleutel: Ja
Toegewezen aan: Associatie Universiteit Gent