Zoek expertise
Pia Clercx Universiteit Gent
Liesbeth Clinckemalie KU Leuven
Jan COLPAERT Universiteit Hasselt
Computationele Kankerbiologie en Epigenomica KU Leuven
Verantwoordelijke
Cancers are highly heterogeneous entities, both within a single tumor and across patients. Intratumoral heterogeneity stems from the spectrum of cancer cell clones and the dynamic cellular composition of the tumour microenvironment. Cross-patient heterogeneity is based on the multitude of cancer cells-of-origin and patient-specific combinations of germline and somatic genetic variants driving the tumorigenesis. Despite recent major ...