Projects
Area-selective deposition: a bottom-up technique for creating nanoscale structures KU Leuven
The miniaturization of dimensions of nano-electronic device brings major challenges to the patterning process by lithography. In addition to scaling resolution, the accurate pattern placement is becoming increasingly difficult. The reduction of the active footprint also implies an evolution that involves 3D structures with high aspect ratio and complex shape. This evolution poses major challenges for the fabrication processes. Therefore, ...
PPP2R5D-related neurodevelopmental disorders: pathologic mechanisms and therapeutic avenues KU Leuven
Reversible protein phosphorylation is a majorly important post-translational modification involved in cell regulation and signaling. Dysfunctions of the kinases or phosphatases involved often result in human pathologies, including cancer, diabetes, immunologic and neurologic disorders. For more than 20 years, we have studied in our lab, the structure, function and regulation of Protein Phosphatase 2A (PP2A), the major family of ...
Ancient Wisdom and Platonism KU Leuven
The project aims at offering an innovative perspective on the reception of Plato by exploring ‘Platonist theories of ancient wisdom’. Specifically, it investigates how philosophers during the Roman Imperial Era (1st c. BC to 2nd c. AD) construed Plato’s place in history and relationship with earlier wisdom traditions. Through identifying, translating and analysing relevant, often underexplored writings of ten Platonist philosophers, it ...
Emerging challenges Concerning the Widening Scope of Prenatal Screening: A Guiding Ethical Framework KU Leuven
This project will focus on the ethical and societal challenges that arise in light of the widening scope of prenatal screening. How broad do we, as a society or individual, want prenatal screening panels to be? Non-invasive prenatal testing (NIPT) comprises a set of different technologies and techniques by which cell-free fetal DNA can be analyzed from a maternal blood sample in early pregnancy. Initially, NIPT was used to detect trisomies ...
Operator algebras, discrete quantum groups and C*-tensor categories KU Leuven
In recent years, the first examples of discrete quantum groups with Kazhdan's property (T) were discovered. The first goal of this PhD research project is to develop a systematic approach using geometric group theory to put these examples in a conceptual setting. This should in particular allow to construct the first examples having a single self-adjoint generator, and thus provide very interesting examples of trivalent categories. Using ...
Identification of drug resistance mechanisms and acquired sensitivities in resistant cancer cells using genome-wide CRISPR-mediated screens KU Leuven
Multidrug resistance is a major issue in the cancer field. To counter this problem, extensive research unravelling the molecular mechanisms underlying multidrug resistance is highly needed. This enables the discovery of biomarkers and facilitates the identification of novel drug targets. For this purpose, genome-wide CRISPR screens, based on gene activation and gene knock-out, will be implemented. In this way, resistance mechanisms to ...
Topics in Empirical Industrial Organization KU Leuven
In this thesis, I will cover three topics in empirical industrial organisation. More specifically, this paper will focus on competition in markets related to the energy sector. The first chapter goes into strategic behavior in the Belgian wholesale electricity market, where firms can exercise market power by creating artificial scarcity.
New insights into strategic HRM: a configurational and Bayesian network approach to HR practices, organization of work and leadership KU Leuven
Research in Strategic HRM has mainly focused on the relationship between HR practices and firm performance. In this project, we argue that this focus is one-sided and too simplistic. First, next to HR practices, the organization of work and leadership should be considered, as they also influence employees' behavior and therefore drive firm performance. Second, in an era of sustainable and employee-centred HRM, research should not only focus ...