Neuro-immune mechanisms of visceral and respiratory hypersensitivity KU Leuven
Translational Research in GastroIntestinal Disorders, Allergy and Clinical Immunology Research Group, Laboratory of Ion Channel Research (VIB-KUÂ Leuven), Laboratory of Virology and Chemotherapy (Rega Institute)
Airway hyperreactivity and irritable bowel syndrome are common diseases characterized by mucosal irritation and visceral pain, leading to reduced quality of life and a substantial economic burden. Current therapies are however limited, mainly due to a lack of understanding how sensory neurons become hypersensitive to airborne contaminants, food components, cold and chemical factors produced by the microbiota lining the airways and gut mucosa. ...