Intra-host evolution of Lassa virus during acute infection and virus persistence KU Leuven
Lassa virus (LASV) is an endemic virus in West Africa that infects hundreds of thousands of individuals each year. Humans primarily become infected through contact with rodents of the genus Mastomys that shed virus in their urine and faeces. About 80% of people who become infected remain asymptomatic, but 1 in 5 LASV infections result in an acute viral haemorrhagic illness. No effective treatments or vaccines exist and little is known about ...