Publications
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Humoral Immune Response in Calves Vaccinated with Monovalent Vaccines or a Trivalent Combination Thereof and Matching of These Vaccines to the Selected Circulating Foot-and-Mouth Disease Viruses in Ethiopia KU Leuven
Foot-and-mouth disease (FMD) is an endemic, highly contagious, and devastating disease of livestock production in Ethiopia. Control of this disease relies mainly on prophylactic vaccination by willing farmers without a countrywide vaccination program. The objectives of this study were to quantify the humoral immune response and evaluation of the serological relationship of the vaccine strain used with representative field strain isolates. This ...
Comparison of the efficacy of autogenous inactivated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccines with that of commercial vaccines against homologous and heterologous challenges Ghent University
Background: The porcine reproductive and respiratory syndrome virus (PRRSV) is a rapidly evolving pathogen of swine. At present, there is a high demand for safe and more effective vaccines that can be adapted regularly to emerging virus variants. A recent study showed that, by the use of a controlled inactivation procedure, an experimental BEI-inactivated PRRSV vaccine can be developed that offers partial protection against homologous challenge ...
Alternating 3 different influenza vaccines for swine in Europe for a broader antibody response and protection Ghent University
Heterologous prime-boost vaccination with experimental or commercial influenza vaccines has been successful in various animal species. In this study, we have examined the efficacy of alternating 3 different European commercial swine influenza A virus (swIAV) vaccines: the trivalent Respiporc® FLU3 (TIV), the bivalent GRIPORK® (BIV) and the monovalent Respiporc® FLUpan H1N1 (MOV). Five groups of 6 pigs each received 3 vaccinations at 4–6 week ...
Mucosal vaccination against periodontal disease : unexploited potential for veterinary and human oral medicine Ghent University
Periodontal disease is one of the most prevalent diseases in humans, dogs, and cats, imposing a significant burden on human and animal health. Control options remain nonspecific, time-consuming, and costly; largely relying on the removal of dental plaque and calculus by mechanical debridement. However, while this reduces the formation of a disease-triggering dysbiotic biofilm, it does not directly affect the latent dysregulated inflammatory ...
Integrating a community-based continuous mass dog vaccination delivery strategy into the veterinary system of Tanzania Institute of Tropical Medicine
ABSTRACT: Sustained vaccination coverage of domestic dog populations can interrupt rabies transmission. However, challenges remain including low dog owner participation, high operational costs associated with current (centralized and annually delivered (pulse)) approaches and high dog population turnover. To address these challenges an alternative (community-based continuous mass dog vaccination (CBC-MDV)) approach was designed. We ...
The transfer of East Coast fever immunisation to veterinary paraprofessionals in Zambia Institute of Tropical Medicine
The use of statistical and simulation modelling as decision support tools in veterinary public health Institute of Tropical Medicine
In this thesis, the Ecuadorian case of two livestock-related neglected zoonoses (brucellosis and cysticercosis) is treated. We tried to find and evaluate their relationships with components of food security, such as livestock populations, adequate sanitation and biological variability within livestock species. Generally, in extensive and small-holder livestock systems in developing countries, there is a carelessness when it comes to the ...
Perspectives for improvement of Mycoplasma hyopneumoniae vaccines in pigs Ghent University
Mycoplasma hyopneumoniae (M. hyopneumoniae) is one of the primary agents involved in the porcine respiratory disease complex, economically one of the most important diseases in pigs worldwide. The pathogen adheres to the ciliated epithelium of the trachea, bronchi, and bronchioles, causes damage to the mucosal clearance system, modulates the immune system and renders the animal more susceptible to other respiratory infections. The pathogenesis ...